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Clinical trial condition

Hemoglobinopathies

Explore clinical trials studying Hemoglobinopathies. Study availability and eligibility vary by location and protocol.

1,050 public trials 170 recruiting studies
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Hemoglobinopathies trial results

Active, Not Recruiting

Safety and Efficacy Evaluation of BRL-101 in Subjects With Transfusion-Dependent β-Thalassemia

NCT05577312

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +8 more
Locations
  • Nanfang Hospital, Southern Medical University Guangzhou, Guangdong, China
  • Sun Yat-Sen Memorial Hospital of Sun Yat-Sen Universit Guanzhou, Guangdong, China
  • Shenzhen Children 's Hospital Shenzhen, Guangdong, China
  • No. 923 Hospital of Joint Support Force of Chinese People 's Liberation Army Hospital Nanning, Guangxi, China
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Active, Not Recruiting

Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients

NCT03814746

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +9 more
Locations
  • Childrens Healthcare of Atlanta Atlanta, Georgia, United States
  • Boston Medical Center Boston, Massachusetts, United States
  • Levine Cancer Insitute Carolinas Healthcare System Charlotte, North Carolina, United States
  • Univ of Tenn Health Sciences Ctr Memphis, Tennessee, United States
View all 59 locations
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Active, Not Recruiting

CINC424A2X01B Rollover Protocol

NCT02386800

Conditions
Acute Myeloid Leukemia, Anemia, Anemia, Hemolytic, +31 more
Locations
  • Novartis Investigative Site Darlinghurst, New South Wales, Australia
  • Novartis Investigative Site Herston, Queensland, Australia
  • Novartis Investigative Site Wooloongabba, Queensland, Australia
  • Novartis Investigative Site Bedford Park, South Australia, Australia
View all 97 locations
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Active, Not Recruiting

Early Check: Expanded Screening in Newborns

NCT03655223

Conditions
17 Alpha-Hydroxylase Deficiency, 3-Hydroxy-3-Methylglutaric Aciduria, 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency, +456 more
Locations
  • RTI International Research Triangle Park, North Carolina, United States
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Active, Not Recruiting

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

NCT06421636

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +8 more
Locations
  • Weill Cornell Medicine New York, United States
  • K Eristavi National Center of Experimental and Clinical Surgery Tbilisi, Georgia
  • Medinvest Institute of Hematology and Transfusiology Limited Tbilisi, Georgia
  • Children's Hospital Agia Sophia Athens, Attica, Greece
View all 26 locations
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Active, Not Recruiting

Realizing Effectiveness Across Continents With Hydroxyurea (REACH)

NCT01966731

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +7 more
Locations
  • Hospital Pediátrico David Bernardino Luanda, Angola
  • Centre Hospitalier Monkole Kinshasa, Democratic Republic of the Congo
  • KEMRI/Wellcome Trust Research Kilifi, Kenya
  • Ministry of Health Mbale Regional Hospital Mbale, Uganda
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Active, Not Recruiting

A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP)

NCT05031780

Conditions
Anemia, Anemia, Hemolytic, Anemia, Hemolytic, Congenital, +7 more
Locations
  • University of California San Diego La Jolla, California, United States
  • UCLA Health Los Angeles, California, United States
  • Children's Hospital Oakland Oakland, California, United States
  • University of Connecticut Health Center Farmington, Connecticut, United States
View all 91 locations
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