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OpenTrials

Clinical trial condition

Alagille Syndrome

Explore clinical trials studying Alagille Syndrome. Study availability and eligibility vary by location and protocol.

21 public trials 4 recruiting studies
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Alagille Syndrome trial results

Completed

Efficacy and Safety of Odevixibat in Patients With Alagille Syndrome

NCT04674761

Conditions
Abnormalities, Multiple, Alagille Syndrome, Bile Duct Diseases, +11 more
Locations
  • University of California - San Francisco San Francisco, California, United States
  • Johns Hopkins Hospital Baltimore, Maryland, United States
  • Boston Children's Hospital Boston, Massachusetts, United States
  • Children's Mercy Hospital and Clinics Kansas City, Missouri, United States
View all 32 locations
View Trial Details
Completed

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Subjects With Alagille Syndrome (ALGS)

NCT02047318

Conditions
Abnormalities, Multiple, Alagille Syndrome, Bile Duct Diseases, +11 more
Locations
  • Birmingham Children's Hospital Birmingham, West Midlands, United Kingdom
  • Leeds Teaching Hospital NHS Trust Leeds, West Yorkshire, United Kingdom
  • Kings College Hospital London, United Kingdom
View Trial Details
Completed

Safety and Efficacy Study of LUM001 (Maralixibat) With a Drug Withdrawal Period in Participants With Alagille Syndrome (ALGS)

NCT02160782

Conditions
Abnormalities, Multiple, Alagille Syndrome, Bile Duct Diseases, +11 more
Locations
  • Children's Hospital Westmead Westmead, New South Wales, Australia
  • The Royal Children's Hospital Melbourne Parkville, Victoria, Australia
  • Cliniques Universitaires Saint-Luc Brussels, Belgium
  • Hopital Femme Mere Enfant De Lyon Bron, France
View Trial Details
Completed

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Pediatric Subjects With Alagille Syndrome

NCT02117713

Conditions
Abnormalities, Multiple, Alagille Syndrome, Bile Duct Diseases, +11 more
Locations
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • University of California at San Francisco Children's Hospital San Francisco, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • Riley Hospital for Children Indianapolis, Indiana, United States
View Trial Details
Completed

Evaluation of LUM001 in the Reduction of Pruritus in Alagille Syndrome

NCT02057692

Conditions
Abnormalities, Multiple, Alagille Syndrome, Bile Duct Diseases, +11 more
Locations
  • Children's Hospital Los Angeles Los Angeles, California, United States
  • University of California at San Francisco San Francisco, California, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • Children's Healthcare of Atlanta Atlanta, Georgia, United States
View all 13 locations
View Trial Details
Completed

Validation of the Itch Reported Outcome (ItchRO) Diaries in Pediatric Cholestatic Liver Disease

NCT02131623

Conditions
Abnormalities, Multiple, Alagille Syndrome, Bile Duct Diseases, +13 more
Locations
  • Phoenix Childrens Hospital Phoenix, Arizona, United States
  • Children's Hospital Colorado Aurora, Colorado, United States
  • St. Louis Children's Hospital St Louis, Missouri, United States
  • The Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States
View Trial Details

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