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Recruiting

Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

NCT06203600

Conditions
Adenocarcinoma Of Esophagus, Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, +14 more
Locations
  • Baptist Health Medical Center - Little Rock Little Rock, Arkansas, United States
  • University of Arkansas for Medical Sciences Little Rock, Arkansas, United States
  • Kaiser Permanente-Anaheim Anaheim, California, United States
  • Kaiser Permanente-Baldwin Park Baldwin Park, California, United States
View all 374 locations
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Recruiting

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

NCT05677490

Conditions
Adenocarcinoma Of Esophagus, Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, +13 more
Locations
  • University of Alabama at Birmingham Cancer Center Birmingham, Alabama, United States
  • Anchorage Associates in Radiation Medicine Anchorage, Alaska, United States
  • Anchorage Radiation Therapy Center Anchorage, Alaska, United States
  • Alaska Breast Care and Surgery LLC Anchorage, Alaska, United States
View all 794 locations
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Completed

Olaparib and Ramucirumab in Treating Patients With Metastatic or Locally Recurrent Gastric or Gastroesophageal Junction Cancer That Cannot Be Removed by Surgery

NCT03008278

Conditions
Digestive System Diseases, Digestive System Neoplasms, Esophageal Diseases, +21 more
Locations
  • City of Hope Corona Corona, California, United States
  • City of Hope Comprehensive Cancer Center Duarte, California, United States
  • City of Hope Antelope Valley Lancaster, California, United States
  • University of California Davis Comprehensive Cancer Center Sacramento, California, United States
View all 32 locations
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Active, Not Recruiting

Berzosertib and Irinotecan in Treating Patients With Progressive, Metastatic, or Unresectable TP53 Mutant Gastric or Gastroesophageal Junction Cancer

NCT03641313

Conditions
Clinical Stage III Gastric Cancer AJCC v8, Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage IV Gastric Cancer AJCC v8, +5 more
Locations
  • City of Hope Comprehensive Cancer Center Duarte, California, United States
  • Los Angeles General Medical Center Los Angeles, California, United States
  • USC / Norris Comprehensive Cancer Center Los Angeles, California, United States
  • UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California, United States
View all 31 locations
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Active, Not Recruiting

Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery

NCT04391049

Conditions
Advanced Esophageal Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma, Carcinoma, +36 more
Locations
  • City of Hope Comprehensive Cancer Center Duarte, California, United States
  • City of Hope South Pasadena South Pasadena, California, United States
  • City of Hope Upland Upland, California, United States
  • Moffitt Cancer Center Tampa, Florida, United States
View all 17 locations
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Active, Not Recruiting

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

NCT04460937

Conditions
Adenocarcinoma Of Esophagus, Brain Diseases, Brain Neoplasms, +80 more
Locations
  • City of Hope Comprehensive Cancer Center Duarte, California, United States
  • Northwestern University Chicago, Illinois, United States
  • University of Kentucky/Markey Cancer Center Lexington, Kentucky, United States
  • Ohio State University Comprehensive Cancer Center Columbus, Ohio, United States
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Active, Not Recruiting

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

NCT04704661

Conditions
Advanced Breast Carcinoma, Advanced Colon Carcinoma, Advanced Colorectal Carcinoma, +80 more
Locations
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine, California, United States
  • Los Angeles General Medical Center Los Angeles, California, United States
  • USC / Norris Comprehensive Cancer Center Los Angeles, California, United States
  • UC Irvine Health/Chao Family Comprehensive Cancer Center Orange, California, United States
View all 23 locations
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Active, Not Recruiting

A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer

NCT06251973

Conditions
Adenocarcinoma Of Esophagus, Advanced Unresectable Gastric Adenocarcinoma, Digestive System Diseases, +22 more
Locations
  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) Basking Ridge, New Jersey, United States
  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities) Middletown, New Jersey, United States
  • Memorial Sloan Kettering Bergen (Limited Protocol Activities) Montvale, New Jersey, United States
  • Memorial Sloan Kettering Suffolk-Commack (Limited protocol activities) Commack, New York, United States
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