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NCT05189925
- Conditions
- Chronic Disease, Chronic Granulomatous Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +16 more
- Locations
-
- National Institutes of Health Clinical Center Bethesda, Maryland, United States
Recruiting
Lentiviral Gene Therapy for CGD
NCT03645486
- Conditions
- Chronic Disease, Chronic Granulomatous Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +12 more
- Locations
-
- Shenzhen Geno-immune Medical Institute Shenzhen, Guangdong, China
NCT07284641
- Conditions
- 22q11 Deletion Syndrome, Abnormalities, Multiple, Blood Protein Disorders, +56 more
- Locations
-
- UPMC Children's Hospital of Pittsburgh Pittsburgh, Pennsylvania, United States
- Conditions
- Chronic Disease, Chronic Granulomatous Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +12 more
- Locations
-
- National Institutes of Health Clinical Center Bethesda, Maryland, United States
Enrolling by Invitation
A Study of the Safety and Efficacy of Prime Editing (PM359) in Participants With p47phox Autosomal Recessive Chronic Granulomatous Disease (CGD )
NCT06559176
- Conditions
- Chronic Disease, Chronic Granulomatous Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +12 more
- Locations
-
- University of California Los Angeles Medical Center Los Angeles, California, United States
- NIH Clinical Center Bethesda, Maryland, United States
- The Children's Hospital at Tristar Medical Group/Sarah Cannon Center for Blood Cancers Nashville, Tennessee, United States
- CHU - Sainte Justine Hospital Montreal, Quebec, Canada
Enrolling by Invitation
pCCLCHIM-p47 (Lentiviral Vector Transduced CD34 Plus Cells) in Patients With p47 Autosomal Recessive Chronic Granulomatous Disease (AR-CGD)
NCT06253507
- Conditions
- Autosomal Recessive, Chronic Disease, Chronic Granulomatous Disease, +15 more
- Locations
-
- National Institutes of Health Clinical Center Bethesda, Maryland, United States
Completed
Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer
NCT02108028
- Conditions
- Cancer, Chronic Disease, Chronic Granulomatous Disease, +17 more
- Locations
-
- Children's Hospital of Orange County Orange, California, United States
- Childrens National Medical Center Washington D.C., District of Columbia, United States
- Moffitt Cancer Center Tampa, Florida, United States
- The Johns Hopkins Hospital Baltimore, Maryland, United States
NCT02116764
- Conditions
- Chronic Disease, Chronic Granulomatous Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +13 more
- Locations
-
- National Institutes of Health Clinical Center Bethesda, Maryland, United States
NCT00368446
- Conditions
- Abnormalities, Multiple, Actinomycetales Infections, Bacterial Infections, +39 more
- Locations
-
- National Institutes of Health Clinical Center Bethesda, Maryland, United States
Completed
Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease With Inflammatory Complications
NCT05104723
- Conditions
- Chronic Disease, Chronic Granulomatous Disease, Colitis, +26 more
- Locations
-
- National Institutes of Health Clinical Center Bethesda, Maryland, United States
NCT03983837
- Conditions
- Chronic Disease, Chronic Granulomatous Disease, Colitis, +22 more
- Locations
-
- National Institutes of Health Clinical Center Bethesda, Maryland, United States
Completed
Baby Detect : Genomic Newborn Screening
NCT05687474
- Conditions
- 3-Hydroxy 3-Methyl Glutaric Aciduria, 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency, 3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 Deficiency, +368 more
- Locations
-
- CRMN, Hôpital La Citadelle Liège, Wallonia, Belgium
NCT03513328
- Conditions
- Acquired Anemia Hemolytic, Acquired Neutropenia in Newborn, Acquired Thrombocytopenia, +82 more
- Locations
-
- UF Health Shands Children's Hospital Gainesville, Florida, United States
NCT01998633
- Conditions
- Blood Protein Disorders, Chronic Active Epstein-Barr Virus Infection, Chronic Disease, +26 more
- Locations
-
- University of Alabama at Birmingham Birmingham, Alabama, United States
- Children's National Medical Center Washington D.C., District of Columbia, United States
- Children's Healthcare of Atlanta Atlanta, Georgia, United States
- Ann and Robert H. Lurie Children's Hospital of Chicago Chicago, Illinois, United States
NCT03548818
- Conditions
- Chronic Disease, Chronic Granulomatous Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +12 more
- Locations
-
- University of Colorado Anschutz Medical Campus Aurora, Colorado, United States
NCT00799071
- Conditions
- Chronic Disease, Chronic Granulomatous Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +12 more
- Locations
-
- Radboud University Medical Centre Nijmegen Nijmegen, Gelderland, Netherlands
- AMC Amsterdam, Netherlands
NCT04136028
- Conditions
- Chronic Disease, Chronic Granulomatous Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +12 more
- Locations
-
- Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology Moscow, Russia
NCT01917708
- Conditions
- Albinism, Anemia, Anemia, Aplastic, +80 more
- Locations
-
- Children's Healthcare of Atlanta Atlanta, Georgia, United States
Completed
Effect of IFN-γ on Innate Immune Cells
NCT02609932
- Conditions
- Chronic Disease, Chronic Granulomatous Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +12 more
- Locations
-
- University of Colorado Denver, Anschutz Medical Campus Aurora, Colorado, United States
NCT00578643
- Conditions
- Chronic Disease, Chronic Granulomatous Disease, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, +12 more
- Locations
-
- Texas Children's Hospital Houston, Texas, United States