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Completed

NCT Number: NCT07218861

You Belong and You Matter: An Exploration of Self-injurious Thoughts and Behaviors in LGTBQ+ Individuals

Individuals with minoritized sexual and gender identities (i.e., LGBTQ+ individuals) are at a greater risk for self-injurious thoughts and behaviors than their cisgender, straight peers (Haas et al., 2010; Liu et al., 2017; Gorse, 2022). There is a dearth of empirically supported interventions for self-injurious thoughts and behaviors (Linehan, 2008; Riblet et al., 2017), and those that exist are not tailored to people in the LGBTQ+ community (Gorse, 2022; Haas et al., 2010). Therefore, the aim of this study is to test the effectiveness of a brief LGBTQ+ affirming text message intervention in reducing self-injurious thoughts and behaviors among LGBTQ+ individuals.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Louisville

Louisville, Kentucky, 40208, United States

About this study

Scope of the work

LGBTQ+ individuals are at a greater risk for self-injurious thoughts and behaviors than their cisgender, straight peers. Despite this known risk, there are no culturally sensitive empirically supported treatments for self-injurious thoughts and behaviors for LBGTQ+ individuals. Therefore, the aim of this study is to test the effectiveness of a brief LGBTQ+ affirming text message intervention in reducing self-injurious thoughts and behaviors among LGBTQ+ individuals. Participants will be 100 LGBTQ+ adults who report self-injurious thoughts and/or behaviors in the last month. All participants will do 14 days of ecological momentary assessment (brief assessments on their mobile device 5 times a day) pre-randomization. After this period, half the participants will receive 2 brief affirming messages a day (morning and afternoon) for 14 days, and half of the participants will receive no messages for 14 days. The text messages will be designed to communicate belonging and importance for LGBTQ+ individuals in society (e.g., "There are over 9,000,000 LGBTQ+ people in the United States. You are not alone". Then all participants will complete another 14 days of ecological momentary assessment. During the assessment periods, participants will report on experiences of discrimination, belongingness, perceived burdensome, and self-injurious thoughts. We predict that participants in the mobile health condition will have a significant decrease in self-injurious thoughts and behaviors from pre- to post-intervention, whereas there will be no change in the control condition. We also predict that participants in the mobile health condition will lead to a significant decrease in thwarted belongingness and perceived burdensomeness. Finally, we predict that our intervention will help break the link between of experiences discrimination and self-injurious thoughts and behaviors by reducing feelings of thwarted belongingness and perceived burdensomeness in response to sexual and gender minority stress. If the effectiveness of our intervention is supported by the data, this intervention could be scaled up and be made available to the LGBTQ+ community broadly.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • be 18 years or older b) have an LGBTQ+ identity (e.g., a sexual orientation other than exclusively straight and/or a gender identity other than exclusively cisgender) c) report at least one self-injurious thought (e.g., suicidal or nonsuicidal self-injury ideation), or behavior (nonsuicidal self-injury, suicide attempt) in the last month

Exclusion criteria

  • Younger than 18, exclusivilty cisgender, heterosexual, no history of SITB in the last month

Treatment and study plan

Supportive Messages

Behavioral

Participants received 28 supportive messages (2 per day) for 14 days

Primary outcomes

  1. Self-injurious thoughts and behavior

    Time frame: last two hours

    self reported

Sponsors and collaborators

Lead sponsor

Konrad Bresin

Other

Registry information

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Oct 20, 2025
Registry last updated
May 11, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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