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Completed

NCT Number: NCT00349869

Yoga for Rheumatoid Arthritis

The purpose of this study is to evaluate the impact of yoga on inflammatory arthritis and knee osteoarthritis.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Johns Hopkins Arthritis Center, 5501 Hopkins-Bayview Circle, Ste 1B.14

Baltimore, Maryland, 21224, United States

About this study

Yoga is a set of ancient Indian theories and practices, focusing on unifying mind, body, and spirit, and promoting strength, balance, and flexibility. The physical aspect of yoga includes poses, breathing techniques, and relaxation. Inflammatory arthritis, a chronic disease characterized by inflammation of the lining of the joints, can cause long-term joint damage, resulting in chronic pain, loss of function, and disability.

The primary objective of this study is to learn how people with inflammatory arthritis and knee osteoarthritis respond to an exercise program of yoga. To accomplish this, 30 persons with inflammatory arthritis or knee osteoarthritis will be randomly assigned to one of two groups. Group one will begin an immediate 8-week program of yoga classes consisting of 60-minute sessions, twice a week. Group two, or the "waitlist" control group, will receive 8 weeks of arthritis education followed by the same 8-week yoga program as group one. Participants also will have blood drawn, and complete various tests. The yoga classes will be taught by an experienced, certified yoga instructor, and are designed especially for the needs of people with inflammatory arthritis and knee osteoarthritis.

This study will provide important data on integrating mind-body activities into the treatment of inflammatory arthritis and knee osteoarthritis.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18+ (RA only upper age limit 70)
  • Confirmed or probable OA (using pre-specified criteria) OR Rheumatoid arthritis (participation approved by rheumatologist)
  • Currently sedentary (physically active for 20 min < 3times/week)

Exclusion criteria

  • Inability to ambulate without use of assistive device
  • Uncontrolled high blood pressure or existing heart condition
  • Co-morbid inflammatory condition with overlapping symptoms (i.e., fibromyalgia)
  • Surgery within 6 months

Treatment and study plan

Yoga

Behavioral

8-week yoga program.

Primary outcomes

  1. Physical Health

    Time frame: baseline, post intervention, follow-up

    Assessed using SF36 Physical Component Score

Secondary outcomes

  1. Mobility/Fitness

    Time frame: baseline, posttest, follow-up

    Change in flexibility, balance, strength, walk time

  2. RA Disease Activity

    Time frame: baseline, post intervention, follow-up

    DAS28 CRP score

  3. Psychological Function

    Time frame: baseline, , posttest, follow-up

    Change in SF36 MCS, CES-D, PANAS, Perceived Stress and Arthritis Self Efficacy

  4. HRQL

    Time frame: baseline, post intervention, follow-up

    Change in SF36 domains

Sponsors and collaborators

Lead sponsor

Johns Hopkins University

Other

Collaborators

  • National Center for Complementary and Integrative Health (NCCIH)

Registry information

Official study title

Yoga for Persons With Rheumatoid Arthritis

Important dates

Study start
2006
Primary completion
2010
Study completion
2011
First posted
Jul 10, 2006
Registry last updated
Jun 18, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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