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Active, Not Recruiting

NCT Number: NCT02609750

WorkUp. Structured Care With Workplace Interventions to Improve Work Ability in Patients With Neck and/or Low Back Pain

WorkUp is a prospective cluster randomised controlled trial in primary care. The main purpose is to investigate effects of early structured care based on screening of red flags (signs of serious medical conditions/disease), yellow flags (psychosocial factors, attitude to pain) and blue flags (workplace related factors) and including a workplace intervention according to the method "Convergence Dialogue Meetings" (CDM) for improving work ability, in comparison with treatment as usual, in patients with neck and/or back pain.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Age range

18 year–67 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Musculoskeletal disorders are the most common reasons for sick leave in western countries. Identifying risk factors and predictors for a stable return to work (RTW ) is essential. An evidence-based safe care includes systems for detecting medical conditions with urgent need for care (red flags) and psycho-social risk factors (yellow flags). To maintain work ability, also requires different capacities related to work demands, (physical, mental and social) as well as work environment aspects covered by a "blue flag system".

Since motivation is assumed to drive and sustain human behaviour, patients with back pain seek health care when motivation reaches a threshold level. Patients want to be examined, get treatment and self-care advice to resume normal daily activities. This might lead to improved long-standing results in terms of health, function and work ability.

The investigators hypothesize that WorkUp, a timely tailor-made and evidence-based intervention leads to a faster recovery of health, function and RTW as compared to standard care. This includes the identification of both the patient's risk factors (red, yellow and blue flags) and motivational factors. Based on this screening, a structured tailored intervention will be offered. The WorkUp model comprise of evidence-based treatment and interaction between patient, health care and work place interventions.

The main purpose is to test WorkUp in a comparison study with treatment as usual (TAU) in primary health care (PHC).

Design: A prospective paire wise cluster randomized trial in PHC including a one year clinical follow-up and a three year register follow-up.

Intervention: Through a flow chart the investigators in detail specify the medical and work place interventions (all according to evidence-based guidelines). Red, yellow and blue flags, and motivational factors are identified in a screening investigation. The aim of the screening is to individually tailor the rehabilitation interventions. Physiotherapy interventions are based on a bio-psychosocial and cognitive behavioural therapy perspective. Behavioural medicine treatment principles will include careful examination and treatments such as advice to stay active, instructions, OMI, OMT, MDT. The investigators apply interventions based on ergonomics, motivational factors and work place changes according to Convergence Dialogue Meetings(CDM). CDM is a three step structured dialogue and meeting model supporting the patient, health care professionals and employer to summarize concrete suggestions to support a RTW .

TAU patients follow the PHC's standard schedule and procedures including the so called rehabilitation guarantee.

For each patient all treatment measures are recorded in a protocol.

A power analysis indicated that the investigators needed to recruit a minimum of 20 PHCs and 500 patients.

This type of structured routine primary care can facilitate an adequate treatment for patients with musculoskeletal pain and how to allocate sparse resources. If beneficial results emerge a structured implementation program will follow.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • acute and subacute neck and/or back pain (less than three months of duration)
  • a working history of at least four weeks during the last year
  • being at risk for sick leave according to the short form of the Örebro Musculoskeletal Pain Screening Questionnaire (ÖMPSQ) (cut off >40)
  • if sickness absent < 60 days.

Exclusion criteria

  • identified abuse
  • retirement pension
  • ongoing acute medical treatment
  • pregnancy

Treatment and study plan

Structured care & workplace intervention

Other

In addition to structured care a workplace intervention named Convergence Dialogue Meetings (CDM) are carried out. CDM is a three step structured dialogue and meeting model supporting the patient, health care professionals and employer to summarize concrete suggestions to support sustainable work ability and a return to work if sick listed.

Treatment as Usual

Other

Patients will follow the primary health care's standard time schedule and procedures as of ordinary care and the rehabilitation guarantee. For each patient all treatment measures are recorded in a manual, regarding number of treatments, time used per treatment and type of treatment.

Primary outcomes

  1. Work ability

    Time frame: Changes from baseline to after treatment (3, 6, 12 months and 2 and 3 years)

    Work ability (defined as being at work or being eligible to the labour market during at least four weeks in a row) and time of sickness absence and Return to work. Year 2 and 3 follow-up by register data

Secondary outcomes

  1. Health-related quality of life

    Time frame: Changes from baseline to after treatment (3, 6 and 12 months)

    Measured by EQ-5D (Euroqol 2011 EQ-5D)

  2. Functional ability

    Time frame: Changes from baseline to after treatment (3, 6 and 12 months)

    Measured by the Oswestry Disability Index (ODI) in low back pain patients (Fairbank & Pynsent 2000) and by the Neck Disability Index (NDI) in patients with neck pain (MacDermid et al 2009)

  3. Pain (distribution and intensity)

    Time frame: Changes from baseline to after treatment (3, 6 and 12 months)

    Measured by the Pain mannequin (Bergman et al 2001) and VAS (Sieper et al 2009)

  4. Physical and psycho-social work environment

    Time frame: Changes from baseline to after treatment (3, 6 and 12 months)

    Measured by questions focusing on known risk factors according to Lindell´s thesis (2010) and the ULF questionnaire

  5. Patient´s satisfaction

    Time frame: Changes from baseline to after treatemnt (3, 6 and 12 months)

    Measured by use of the Client Satisfaction Questionnaire (CSQ) (Bjelland 2002)

Sponsors and collaborators

Lead sponsor

Lund University

Other

Collaborators

  • Blekinge County Council Hospital
  • Kronoberg County Council
  • Region Skane

Registry information

Official study title

WorkUp. Early Structured Care Including Workplace Interventions to Improve Work Ability in Patients With Neck and/or Back Pain. A Prospective Pare Wise Cluster Randomized Controlled Trial in Primary Care With One Year Follow up

Acronym: WorkUp

Important dates

Study start
2013
Primary completion
2015
Study completion
2025
First posted
Nov 20, 2015
Registry last updated
Mar 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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