Wilson's Disease Treated With D-Penicillamine: Characterization of Skin Damage Secondary to Treatment by Measuring Skin Elasticity

Inclusion criteria

Diseased patients :

• Patient over 12 years old
• Patient with Wilson's disease confirmed by genetic analysis
• Patient followed up in the Wilson's Disease Reference Center for his care
• Patient treated with D-Penicillamine
• Patient with no other known elastic tissue pathology

Healthy volunteers :

• Patient over 12 years old
• Patient followed up in the dermatology department of St Etienne University Hospital
• Patient matched on sex and age with a patient from the "Wilson's disease" group
• Patient with no elastic tissue pathology

All patients :

• Patient affiliated to a national social security
• Patient with written informed consent

Exclusion criteria

All patients:

• Patient not taking a treatment (at investigator's discretion) that may modify skin elasticity
• Patient with pathological lesion(s) on forearm or cheek
• Patient with a potentially active/rejuvenative forearm or cheek treatment
• Patient having applied cream and/or make-up to the areas to be molded (forearm and cheek)
• Patient under guardianship
• Patient unable to follow study procedures
• Pregnant or breast-feeding women