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Completed

NCT Number: NCT00388466

Whole Body Vibration - a New Therapeutic Approach to Improve Muscle Function in CF

The purpose of this study is to evaluate the effects of whole body vibration (WBV) on muscle function in adult CF-patients.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CF Center Cologne, University Children's Hospital

Cologne, 50924, Germany

About this study

Cystic Fibrosis (CF) is the most common chronic hereditary disease in Caucasians. Due to improved therapy and better understanding of the disease, life expectancy has risen to an average of 38 years and is continuing to rise. With the increased life-expectancy it becomes even more important to maintain functional activity as part of quality of life. Mechanical stimulation in form of whole body vibration (WBV) is a new type of exercise currently tested in sports, geriatrics and rehabilitation. It has recently been found to be a safe and efficient method to activate muscular activity via stretch reflexes leading to improvement of muscular performance, body balance and physical functioning.

10 patients of the CF Center Cologne, Germany, took part in the Galileo study. They were provided by the vibrating platform (Galileo 2000)for whole body vibration training at home. The patients were standing in an upright position receiving vertical vibration of frequencies between 20-25 Hz. This vibration exercise evokes muscle contractions via stretch reflexes improving muscular activity. The training schedule consisted of three 3-minute sessions twice a day 5 days per week for 3 months.

Every 4 weeks the patients were seen for assessment of muscle function to evaluate the effects of this new intervention.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • clinical diagnosis of Cystic Fibrosis
  • age older than 18 years

Exclusion criteria

  • hypersplenic syndrome
  • acute arthritis or osteomyelitis

Treatment and study plan

GALILEO

Device

Primary outcomes

  1. muscle force at the beginning of the study and after 3 months

  2. muscle power at the beginning of the study and after 3 months

Secondary outcomes

  1. pulmonary function testing at the beginning of the study and after 3 months

Sponsors and collaborators

Lead sponsor

University of Cologne

Other

Registry information

Official study title

Cystic Fibrosis: Improvement of Muscle Force and Function by Whole Body Vibration Exercise

Important dates

Study start
2005
Study completion
2006
First posted
Oct 16, 2006
Registry last updated
Oct 16, 2006

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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