Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07539350

Wellness Enhancement for Caregivers

The purpose of this study is to test WECARE, a seven-week multimedia intervention designed to reduce psychosocial distress and provide education and support for caregivers. This study will include Chinese American family caregivers of persons living with Alzheimer's disease and related dementias. Participants will engage with digital learning materials and supportive resources over the course of the program. The goal is to determine whether this approach improves caregiver well-being and reduces stress related to caregiving.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Caregiver Burden Behavior Behavioral Symptoms Stress, Psychological

Age range

21 year–100 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • currently residing in the United States,
  • self-identify as Chinese or Chinese American and are able to read in Chinese,
  • are 21 years of age or older,
  • own a cellphone and use WeChat, and
  • provide at least 8 hours of care per week to a family member or loved one with ADRD.

Exclusion criteria

(1) evidence of severe cognitive impairment or mental disorders, or (2) the care recipient was receiving hospice care or had a life expectancy of fewer than six months.

Treatment and study plan

WeCare

Behavioral

The 7-week WECARE intervention was designed to improve caregiving skills, alleviate caregiver distress, and enhance the psychosocial well-being of dementia caregivers.

Primary outcomes

  1. Efficacy of Behavioral Intervention in Change From Baseline in Depressive Symptoms

    Time frame: Baseline, and Follow-Up at Weeks 11-12 (4 to 5 weeks after completion of the intervention)

    The baseline and follow-up differences in depressive symptoms will be assessed using the Center for Epidemiologic Studies Depression Scale (CES-D). The CES-D is a 20-item survey instrument designed to measure the frequency and severity of depressive symptoms. The total score is calculated by summing the responses to all 20 items. The total scale ranges from 0 to 60, with higher scores indicating more severe depressive symptoms (a worse outcome). The primary analysis will calculate the difference in this total score between baseline and follow-up.

    adults and dementia caregivers.

Secondary outcomes

  1. Efficacy of Behavioral Intervention in Change From Baseline in Caregiving Burden

    Time frame: Baseline, and Follow-Up at Weeks 11-12 (4 to 5 weeks after completion of the intervention)

    The baseline and follow-up differences in caregiving burden will be assessed using the 12-item Zarit Burden Interview (ZBI-12). The ZBI-12 is designed to measure the subjective physical, psychological, and social burden experienced by caregivers. Each item is rated on a 5-point scale from "never" (0) to "nearly always" (4), The total score is calculated by summing the responses to all 12 items. The total scale ranges from 0 to 48, with higher scores indicating greater caregiving burden (a worse outcome). The primary analysis will calculate the difference in this total score between baseline and follow-up.

Other outcomes

  1. Efficacy of Behavioral Intervention in Change From Baseline in Life Satisfaction

    Time frame: Baseline, and Follow-Up at Weeks 11-12 (4 to 5 weeks after completion of the intervention)

    The baseline and follow-up differences in life satisfaction will be assessed using the Satisfaction with Life Scale (SWLS). The SWLS is a 5-item survey instrument designed to measure a person's global cognitive judgments of satisfaction with their life. The total score is calculated by summing the responses to all 5 items. The total scale ranges from 0 to 30, with higher scores indicating greater life satisfaction (a better outcome). The primary analysis will calculate the difference in this total score between baseline and follow-up.

  2. Efficacy of Behavioral Intervention in Change From Baseline in Caregiving Mastery

    Time frame: Baseline, and Follow-Up at Weeks 11-12 (4 to 5 weeks after completion of the intervention)

    The baseline and follow-up differences in caregiving mastery will be assessed using the Caregiving Mastery Scale. This 7-item survey instrument is designed to measure a caregiver's self-perception of their ability to effectively manage caregiving tasks and challenges. The total score is calculated by summing the responses to all 7 items. The total scale ranges from 0 to 28, with higher scores indicating greater caregiving mastery (a better outcome). The primary analysis will calculate the difference in this total score between baseline and follow-up.

  3. Efficacy of Behavioral Intervention in Change in Care-recipient's Problem Behaviors

    Time frame: Baseline, and Follow-Up at Weeks 11-12 (4 to 5 weeks after completion of the intervention)

    The baseline and follow-up differences in care-recipient problem behaviors will be assessed using the Revised Memory and Problem Behavior Checklist (RMBPC). The RMBPC is a 24-item survey instrument designed to measure observable behavioral problems in care recipients across three subdomains: memory-related issues, depressive behaviors, and disruptive behaviors. The total score is calculated by summing the Yes (1) or No (0) responses to all 24 items. The total scale ranges from 0 to 24, with higher scores indicating a higher frequency of problem behaviors (a worse outcome). The primary analysis will calculate the difference in this total score between baseline and follow-up.

  4. Efficacy of Behavioral Intervention in Change From Baseline in Positive Aspect of Caregiving

    Time frame: Baseline, and Follow-Up at Weeks 11-12 (4 to 5 weeks after completion of the intervention)

    The baseline and follow-up differences in caregivers' positive aspects of caregiving will be measured by Positive Aspects of Caregiving Scale, a 9-item scale 5-point Likert scale from 0 to 4, with total scores ranging from 0 to 36, with higher score indicating more positive perception of caregiving. The baseline and follow-up differences in the scores will be calculated.

Sponsors and collaborators

Lead sponsor

George Mason University

Other

Registry information

Official study title

WECARE: A Personalized Intervention for Underserved Chinese American Dementia Caregivers

Acronym: WECARE

Important dates

Study start
2026
Primary completion
2030
Study completion
2030
First posted
Apr 20, 2026
Registry last updated
Apr 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.