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NCT Number: NCT07693504

Weekend Warrior Exercise in Sedentary Female University Students

This single-center, single-blind, three-arm randomized controlled trial aims to compare the effects of weekend-concentrated exercise, regularly distributed exercise, and usual lifestyle on aerobic capacity and skeletal muscle strength in sedentary female university students. Sixty participants aged 18 to 25 years will be randomly assigned in a 1:1:1 ratio to a weekend warrior group, a regular exercise group, or a control group.

The intervention will last 8 weeks. Both exercise groups will complete 150 minutes of moderate-intensity exercise per week, combining resistance exercise and jogging, but the exercise sessions will be distributed differently across the week. The control group will maintain its usual lifestyle without receiving the prescribed exercise intervention.

The primary outcomes are peak oxygen uptake and isokinetic peak torque. Secondary outcomes include body composition, maximal heart rate, maximal power and time to exhaustion, 12-minute run performance, isokinetic mean torque, physical activity, sleep quality, exercise self-efficacy, emotional status, cognitive function, adherence, feasibility, and exercise-related adverse events.

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Key information

Age range

18 year–25 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

About this study

This study is designed to test whether concentrating the recommended weekly exercise volume into a weekend pattern produces comparable benefits to a regularly distributed exercise pattern in sedentary female university students. The intervention emphasizes a dose-matched comparison in which both exercise groups complete the same total weekly exercise duration, while the distribution of exercise sessions differs.

After baseline screening and assessment, participants will be assigned to one of three parallel groups using a 1:1:1 allocation ratio. The weekend warrior group will complete two consecutive exercise days per week, whereas the regularly distributed exercise group will complete three exercise days per week. Both exercise programs will last 8 weeks and include resistance exercise combined with moderate-intensity jogging.

Resistance exercise will primarily target the lower limbs, core, and major muscle groups. Exercises may include squats, lunges, glute bridges, calf raises, and planks, using body weight, elastic bands, or light equipment as appropriate. Jogging may be performed as continuous jogging or a run-walk format according to individual fitness level. Exercise intensity will be monitored using heart rate and rating of perceived exertion. Jogging intensity will generally be maintained at approximately 60% to 75% of maximal heart rate or a rating of perceived exertion of 12 to 14. Each session will include warm-up, supervised exercise, and cool-down activities.

The main contrast between the two exercise interventions is the weekly distribution of exercise rather than total weekly duration. The control group will maintain usual study and lifestyle habits during the 8-week period. Study staff will monitor adherence, perceived exertion, discomfort, and exercise-related events during the intervention. Outcome assessors will be blinded to group allocation when feasible.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female university students aged 18 to 25 years.
  • Self-reported sedentary time of at least 6 hours per day, further assessed using the International Physical Activity Questionnaire (IPAQ).
  • No cardiovascular, pulmonary, neurological, metabolic, or musculoskeletal diseases.
  • Relatively regular menstrual cycles.
  • Able to understand the study procedures, willing to complete the intervention and assessments, and willing to provide written informed consent.

Exclusion criteria

  • Any condition identified through clinical assessment or health screening that makes participation in moderate-intensity exercise or exercise-to-exhaustion testing inappropriate.
  • Participation in regular exercise training, a systematic weight-loss or body-shaping program, or another exercise intervention study within the previous 3 months.
  • Recent substantial body-weight fluctuations that may affect body-composition assessment.
  • Cardiovascular, pulmonary, neurological, metabolic, or musculoskeletal diseases, or current use of medications that may affect exercise performance, heart-rate responses, or muscle function.
  • Irregular menstrual cycles.
  • Inability to complete the 8-week intervention, post-intervention assessments, or required study records.

Treatment and study plan

Weekend Warrior Exercise

Behavioral

Participants will complete an 8-week weekend-concentrated exercise program on two consecutive days per week. On each exercise day, participants will perform 30 minutes of resistance exercise and 45 minutes of moderate-intensity jogging, resulting in 75 minutes per day and 150 minutes per week. Resistance exercises will target the lower limbs, core, and major muscle groups and may include squats, lunges, glute bridges, calf raises, and planks. Jogging intensity will be maintained at approximately 60% to 75% of maximal heart rate or a rating of perceived exertion of 12 to 14. Each session will include warm-up and cool-down activities.

Regularly Distributed Exercise

Behavioral

Participants will complete 150 minutes of moderate-intensity exercise per week for 8 weeks, distributed across three days. Each session will include 20 minutes of resistance exercise targeting the lower limbs, core, and major muscle groups, followed by 30 minutes of jogging. The exercise content, intensity-control principles, and safety requirements will be comparable to those of the weekend warrior group.

Primary outcomes

  1. Change in Peak Oxygen Uptake (VO2peak)

    Time frame: Baseline (week 0) and post-intervention (week 8)

    Peak oxygen uptake will be assessed during a graded cardiopulmonary exercise test. VO2peak will be recorded in milliliters of oxygen per kilogram of body mass per minute (mL/kg/min). The change from baseline to the end of the 8-week intervention will be compared among the three study groups.

  2. Change in Isokinetic Peak Torque

    Time frame: Baseline (week 0) and post-intervention (week 8)

    Skeletal muscle peak torque will be assessed using an isokinetic dynamometer and recorded in Newton-meters (N·m). The change from baseline to the end of the 8-week intervention will be compared among the three study groups.

Secondary outcomes

  1. Change in Body Weight

    Time frame: Baseline (week 0) and post-intervention (week 8)

    Body weight will be measured in kilograms (kg). The change from baseline to the end of the 8-week intervention will be compared among the three study groups.

  2. Change in Body Mass Index

    Time frame: Baseline (week 0) and post-intervention (week 8)

    Body mass index will be calculated as body weight in kilograms divided by height in meters squared (kg/m²). The change from baseline to week 8 will be compared among the three study groups.

  3. Change in Body Fat Percentage

    Time frame: Baseline (week 0) and post-intervention (week 8)

    Body fat percentage will be assessed using body composition analysis and reported as a percentage (%). The change from baseline to week 8 will be compared among the three study groups.

  4. Change in Waist-to-Hip Ratio

    Time frame: Baseline (week 0) and post-intervention (week 8)

    Waist-to-hip ratio will be calculated by dividing waist circumference by hip circumference. The change from baseline to week 8 will be compared among the three study groups.

  5. Change in Maximal Heart Rate

    Time frame: Baseline (week 0) and post-intervention (week 8)

    Maximal heart rate will be recorded during the graded exercise test and reported in beats per minute (bpm). The change from baseline to week 8 will be compared among the three study groups.

  6. Change in Maximal Power at Exhaustion

    Time frame: Baseline (week 0) and post-intervention (week 8)

    The maximal power output achieved during the graded exercise test will be recorded in watts (W). The change from baseline to week 8 will be compared among the three study groups.

  7. Change in Time to Exhaustion

    Time frame: Baseline (week 0) and post-intervention (week 8)

    Time to exhaustion during the graded exercise test will be recorded in seconds. The change from baseline to week 8 will be compared among the three study groups.

  8. Change in 12-Minute Run Distance

    Time frame: Baseline (week 0) and post-intervention (week 8)

    The total distance completed during the 12-minute run test will be recorded in meters (m). The change from baseline to week 8 will be compared among the three study groups.

  9. Change in Isokinetic Mean Torque

    Time frame: Baseline (week 0) and post-intervention (week 8)

    Mean torque will be assessed using an isokinetic dynamometer and reported in Newton-meters (N·m). The change from baseline to week 8 will be compared among the three study groups.

  10. Change in Physical Activity Level Assessed by the International Physical Activity Questionnaire

    Time frame: Baseline (week 0) and post-intervention (week 8)

    Physical activity level will be assessed using the International Physical Activity Questionnaire (IPAQ) and expressed as metabolic equivalent minutes per week (MET-min/week). Higher values indicate a greater level of physical activity.

  11. Exercise Adherence

    Time frame: Throughout the 8-week intervention

    Exercise adherence will be calculated as the number of completed prescribed exercise sessions divided by the total number of prescribed sessions, multiplied by 100, and reported as a percentage. This outcome will be assessed separately in the two exercise groups.

Study contacts

Contact information is provided by the study sponsor or research team.

Kaixiang Zhou

CONTACT

[email protected]

+86 17844597198

Sponsors and collaborators

Lead sponsor

Chongqing Normal University

Other

Registry information

Official study title

Effects of Weekend Warrior Exercise on Aerobic Capacity and Skeletal Muscle Strength in Sedentary Female University Students: A Randomized Controlled Trial

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Jul 9, 2026
Registry last updated
Jul 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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