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NCT Number: NCT07588893

Buerger-Allen Exercises and Peripheral Circulation in Sedentary Office Workers

This study aims to evaluate the acute effects of Buerger-Allen exercises on lower extremity circulation in sedentary office workers. Prolonged sitting is associated with reduced venous return, impaired peripheral circulation, and endothelial dysfunction. Buerger-Allen exercises are simple position-based exercises designed to enhance arterial blood flow, venous return, and tissue perfusion. Thirty-five healthy sedentary adults aged 18 to 45 years will participate in this single-group pretest-posttest clinical trial. Skin surface temperature, capillary refill time, ankle-brachial index, peripheral oxygen saturation, and heart rate will be measured before and after a single 20-minute exercise session. The findings may support the use of Buerger-Allen exercises as a practical, low-cost physiotherapy strategy to improve peripheral circulation and reduce the adverse vascular effects of prolonged sitting.

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Key information

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

Sedentary behavior and prolonged sitting are associated with impaired venous return, reduced peripheral blood flow, endothelial dysfunction, and increased cardiovascular risk. Office workers who remain seated for extended periods may experience lower extremity discomfort, edema, and early circulatory impairment.

Buerger-Allen exercises are position-based therapeutic exercises that involve sequential elevation, dependency, and horizontal rest of the lower limbs. These exercises are designed to promote arterial inflow, facilitate venous return, and enhance tissue perfusion without requiring specialized equipment. Previous studies have demonstrated beneficial effects in patients with peripheral vascular disease and diabetes, but evidence regarding their acute effects in healthy sedentary adults is limited.

This study will use a quasi-experimental single-group pretest-posttest design to investigate the immediate effects of Buerger-Allen exercises on lower extremity circulation in sedentary office workers. A total of 35 participants aged 18 to 45 years will be recruited from Istanbul Gelisim University. All participants will complete a standardized 20-minute Buerger-Allen exercise protocol.

Primary outcome measures will include skin surface temperature assessed with infrared thermometry, capillary refill time, ankle-brachial index, peripheral oxygen saturation, and heart rate. Measurements will be performed at baseline, immediately after the intervention, and 10 minutes after the intervention.

The study is expected to provide evidence regarding the effectiveness of a simple and low-cost physiotherapy intervention for improving peripheral circulation and preventing the adverse vascular effects associated with prolonged sedentary behavior.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy sedentary office workers
  • Age between 18 and 45 years
  • Sitting for at least 6 hours per day for work-related activities
  • Not meeting regular physical activity recommendations
  • Willing to participate voluntarily and provide written informed consent

Exclusion criteria

  • History of peripheral arterial disease, deep vein thrombosis, or other vascular disorders
  • Cardiovascular, neurological, or musculoskeletal conditions that may affect lower extremity circulation or prevent exercise participation
  • Diabetes mellitus
  • Current smoking
  • Pregnancy
  • Use of medications that may significantly affect peripheral circulation
  • Lower extremity injury or surgery within the previous 6 months
  • Participation in regular structured exercise programs

Treatment and study plan

Buerger-Allen Exercise Program

Behavioral

The intervention consists of a standardized Buerger-Allen exercise protocol involving three sequential positions: (1) elevation of the lower limbs above heart level to facilitate venous return, (2) dependency of the lower limbs to promote arterial blood flow, and (3) horizontal supine rest to stabilize circulation. The complete exercise session lasts approximately 20 minutes and is performed once. Lower extremity circulatory parameters are assessed at baseline, immediately after the intervention, and 10 minutes after the intervention.

Primary outcomes

  1. Skin Surface Temperature

    Time frame: Baseline, Immediately After Intervention, and 10 Minutes After Intervention

    Skin surface temperature measured with an infrared thermometer in degrees Celsius (°C). Higher values indicate increased peripheral blood flow and tissue perfusion.

  2. Capillary Refill Time

    Time frame: Baseline, Immediately After Intervention, and 10 Minutes After Intervention

    Capillary refill time measured in seconds. Shorter times indicate improved peripheral microcirculation and tissue perfusion.

Secondary outcomes

  1. Ankle-Brachial Index (ABI)

    Time frame: Baseline, Immediately After Intervention, and 10 Minutes After Intervention

    Ratio of ankle to brachial systolic blood pressure used to assess lower extremity arterial circulation. Higher values within the normal range indicate better arterial perfusion.

  2. Peripheral Oxygen Saturation (SpO₂)

    Time frame: Baseline, Immediately After Intervention, and 10 Minutes After Intervention

    Oxygen saturation measured by pulse oximetry and expressed as a percentage (%). Higher values indicate improved peripheral oxygenation.

  3. Heart Rate

    Time frame: Baseline, Immediately After Intervention, and 10 Minutes After Intervention

    Heart rate measured by pulse oximetry and expressed in beats per minute (bpm).

Study contacts

Contact information is provided by the study sponsor or research team.

Busenur KARAGÖZ, MSc

CONTACT

[email protected]

+90 534 062 71 24

Gökay ÇAKIROĞLU, PT

CONTACT

[email protected]

+90 542 519 42 55

Sponsors and collaborators

Lead sponsor

Istanbul Gelisim University

Other

Registry information

Official study title

Acute Effects of Buerger-Allen Exercises on Lower Extremity Circulatory Parameters in Sedentary Office Workers: A Single-Group Pretest-Posttest Clinical Trial

Acronym: BAE-CIRC

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
May 15, 2026
Registry last updated
May 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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