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Completed

NCT Number: NCT04687527

Vitamin D Levels and Postoperative Pain in Laparoscopic Cholecystectomy

The deficiency of vitamin D is common in patients with gastrointestinal system disorders.

Vitamin D has been associated with chronic non-specific musculoskeletal pain and migraines due to anti-inflammatory effects.

This prospective observational study will undergo elective laparoscopic cholecystectomy surgery between 18 and 65 years, is planned to participate in ASA (American Society of Anesthesiologists) 1-3, 90 volunteer patients.

In preoperative evaluation, the remaining 3 ml of blood was centrifuged from the routine received blood to determine the level of vitamin D will be kept.

Postoperative will be applied to patient controlled analgesia to all patients for 24 hours.

To determine the level of postoperative pain, the visual analog scale (VAS) will be used in the clock unit and at the service 6, 12 and 24 hours.

In this study, the investigators aimed to test the hypothesis of relation to pain and opioid consumption in acute postoperative (24 hours) of perioperative low-vitamin D.

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Key information

Conditions

Vitamin D Deficiency Avitaminosis Deficiency Diseases Malnutrition Neurologic Manifestations Nutrition Disorders Nutritional and Metabolic Diseases Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Postoperative Pain Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Bozok University Medical Center

Yozgat, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Volunteer,
  • Between the Ages Of 18-65,
  • Least Primary School Graduate,
  • Not Using Drugs That May Affect Cognitive Functions,
  • Non-Alcohol Substance Use,
  • Patients Without Psychiatric and Neurological Disease.

Exclusion criteria

  • Those with known psychiatric disease and drugs,
  • Those with an important cardiovascular or central nervous system disease,
  • Patients with pain syndromes or routinely using opioid.

Very urgent patients

Treatment and study plan

Primary outcomes

  1. preoperative Vitamin D Level and postoperative pain in patients to undergo laparoscopic cholecystectomy operation

    Time frame: 6 months

    Correlations of preoperative Vitamin D Level between postoperative pain in patients undergoing laparoscopic cholecystectomy.to undergo laparoscopic cholecystectomy operation

Secondary outcomes

  1. preoperative Vitamin D Level and opioid analgesic consumption

    Time frame: 6 months

    Correlations of preoperative Vitamin D Level between opioid analgesic consumption in patients undergoing laparoscopic cholecystectomy.to undergo laparoscopic cholecystectomy operation

Sponsors and collaborators

Lead sponsor

Bozok University

Other

Registry information

Official study title

Effect of Vitamin D Levels on Postoperative Pain and Narcotic Analgesia in Patients With Laparoscopic Cholecystectomy

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Dec 29, 2020
Registry last updated
Jun 15, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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