Skip to main content
OpenTrials
Completed

NCT Number: NCT06276881

Visual Stimulation for Pain Relief

The goal of this study is to investigate a novel neuromodulatory approach utilizing visual stimulation to impact pain perception in healthy participants.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Pain Neurologic Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Dandelion Science

Hoboken, New Jersey, 07030, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants of both sexes
  • Participants of diverse ethnic and racial backgrounds
  • Participants who speak, read, and understand English and are willing and able to provide written informed
  • 18 to 50 years old

Exclusion criteria

  • Participants with neurologic, endocrine, renal, gastrointestinal, and chronic pain disease
  • Participants who use unprescribed drugs or medications
  • Chronically medicated participants
  • Participants with photosensitivity and epileptic seizures
  • Participants who have undergone major surgery within two months of the experiment date
  • Participants with cardiac disorders
  • Participants who are pregnant
  • Prisoners
  • Participants who are unable to provide consent
  • Participants diagnosed with a psychiatric disorder that is likely to interfere with the conduct of the study
  • Participants with implanted electronic devices of any kind, including pace-makers, electronic infusion pumps, stimulators, defibrillators

Treatment and study plan

Visual stimulation

Behavioral

AI-guided visual stimuli presented on an electronic screen

Primary outcomes

  1. Visual Analog Scale (VAS) Score

    Time frame: Up to 2 hours

    Standard computerized scale of perceived pain level. The scale ranges from 0 to 100, a score of "0" indicating "No Pain" and a score of "100" indicating "Most Pain". Higher score indicates a worse outcome as perceived pain is increasing, lower score indicates a better outcome as perceived pain is decreasing.

  2. Event-related Potential (ERP)

    Time frame: Up to 2 hours

    Evoked event-related neural response to contact heat perception measured by EEG (electroencephalography), P300 component

Sponsors and collaborators

Lead sponsor

Dandelion Science Sàrl

Industry

Collaborators

  • National Institute on Drug Abuse (NIDA)
  • National Institutes of Health (NIH)

Registry information

Official study title

Pain Relief Through Artificial Intelligence (AI) -Guided Dynamic Neuromodulation

Important dates

Study start
2022
Primary completion
2022
Study completion
2023
First posted
Feb 26, 2024
Registry last updated
Aug 7, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.