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OpenTrials
Active, Not Recruiting

NCT Number: NCT06475053

Visual Performance of Center Distance Daily Disposable Multifocal Lenses

The purpose of this study is to compare visual performance (high and low contrast acuity, reading acuity, contrast sensitivity, stereoacuity, accommodative response, eye hand coordination, far near vision, and dynamic vision) between Visioneering Technologies, Inc. NaturalVue Multifocal and CooperVivion MiSight.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Age range

9 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

The Ohio State University College of Optometry

Columbus, Ohio, 43210, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants must satisfy the following conditions for inclusion in the trial:
  • Be between 9 and 30 years of age
  • Sign written Informed Consent/Assent.
  • Spherical Equivalent glasses prescription: -0.50 to -7.00 diopters (D), Astigmatism: ≤ -0.75D, Anisometropia: ≤ 1.00D
  • 20/20 vision in each eye
  • Existing contact lens wearer
  • An eye exam in last 9 months, normal stereoacuity on prior chart (or test if not available)
  • No known ocular disease - anterior or posterior (posterior determined by history/chart)
  • Have an acceptable or optimal fit with test lenses and be willing to wear these lenses as directed for the duration of the study.
  • On examination, have ocular findings considered to be within normal limits.
  • Be willing and able to follow instructions and attend the schedule of follow-up visits.

Exclusion criteria

  • Any of the following will exclude a participant from this trial:
  • Current hard lens wearers
  • Using eye medication contraindicating lens wear such as daily use of artificial tears.
  • Eye injury or surgery within twelve weeks immediately prior to enrollment for this trial.
  • History of corneal refractive surgery
  • Currently enrolled in an ophthalmic clinical trial that could negatively impact corneal or conjunctival health in this trial.
  • Evidence of systemic or ocular abnormality, infection or disease likely to affect successful wear of contact lenses or use of their accessory solutions.
  • Allergy or sensitivity to any product used in this trial.
  • Pre-existing ocular condition that would contraindicate lens wear.
  • Any systemic disease including autoimmune disease, immunocompromising diseases, connective tissue disease, clinically significant atopic diseases, insulin dependent diabetes, use of medications including corticosteroids and antimetabolites that may affect the eye or be exaggerated by wearing contact lenses.
  • Lazy eye (Strabismus or amblyopia)
  • Pupil size < 3.00 mm in either eye in dim light (measured at approximately 10 cd/m2 )

Treatment and study plan

NaturalVue Enhanced Multifocal 1 Day contact lens

Device

Daily disposable multifocal contact lens

MiSight 1 Day contact lens

Device

Daily disposable dual-focus contact lens

Primary outcomes

  1. Comparison of visual performance (high and low contrast acuity) between VTI NaturalVue Enhanced Multifocal and CooperVision MiSight.

    Time frame: 2 months

    log MAR vision scale

Sponsors and collaborators

Lead sponsor

Visioneering Technologies, Inc

Industry

Collaborators

  • Ohio State University

Registry information

Acronym: ViPCD3

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jun 26, 2024
Registry last updated
Sep 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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