Skip to main content
OpenTrials
Active, Not Recruiting

NCT Number: NCT06534580

Virtual Reality for Advanced Cancer Pain

Background

Pain is commonly experienced by people who are living with advanced (incurable) cancer. There is evidence to suggest virtual reality could help to relieve this pain: however, this evidence is poor quality with the intervention poorly defined. A robustly co-designed intervention, with people who have advanced cancer and experience pain, will facilitate a better evidence-base.

Aim

To develop and refine a virtual reality intervention that will help people living with advanced cancer to manage pain.

Objectives

1. Explore and establish key components of a virtual reality intervention for people with advanced cancer in terms of effectiveness, acceptability and feasibility using in-depth interviews and focus groups with people living with advanced cancer and experiencing pain. 2. Develop and manualise a virtual reality intervention using co-design methodology. 3. User-test the intervention to refine further.

Methods

Multi-method design, incorporating multiple stakeholder perspectives, over three phases:

Phase I. Focus groups or individual interviews with a total of 40 people, from four locations (Brighton, Cardiff, Liverpool, & London), who have advanced cancer and experience pain.

They will use the virtual reality intervention and give feedback on what resonated with them and what they would change.

Phase II. Four focus groups (one at each study location) with multiple stakeholders. During this stage, the findings from phase 1 will be presented and a manual will be produced that gives guidelines on use of the virtual reality intervention.

Phase III. Up to 20 people living with advanced cancer and pain will user-test the intervention over an eight-week period. During this phase, the investigators will test if/how often the virtual reality is used as part of routine practice in each site and identify any barriers of use.

Anticipated Impact and Dissemination

1. A robustly co-designed intervention, ready for testing in a larger trial, to assess the clinical and cost effectiveness of virtual reality as a form of pain management. 2. Guidelines for the use of virtual reality in a clinical setting.

The results will be published through academic routes (peer-reviewed publications as well as presented at national and international conferences). The investigators will also work with our group of people with lived experience and an oversight committee to establish the best other routes to disseminate the findings to the public e.g., a social media campaign, leaflets to clinical settings, blog and vlog posts.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients will be considered eligible to participate if:

  • Under the care of the specialist palliative care team or cancer centre
  • A documented diagnosis of advanced cancer (Synonyms: "Palliative", "terminal", "incurable", "treatable but not curable") in their medical notes, confirmed by the clinical team.
  • Adult (aged 18 years or over)
  • Pain score in the last 7 days of ≥1 on Numerical Rating Scale [0-10]
  • Full visual and auditory abilities
  • No restriction in range of head and neck movement
  • Capacity to consent to the study
  • Fluent in English
  • An estimated prognosis of longer than 6 months.

Professional/staff participants will be considered eligible if:

  • a registered healthcare professional (doctors, nurses, allied health professionals, psychologists)
  • employed by the study or location or by the virtual reality company.

Exclusion criteria

Patients will be excluded if:

  • a diagnosis of epilepsy
  • are imminently dying
  • the clinical team feel it would be detrimental to participate
  • do not meet the study inclusion criteria

Professional/staff participants will be excluded if:

  • They are not employed by the study location, or the virtual reality company

We will document reasons for not participating, where offered.

Treatment and study plan

Virtual reality

Device

A range of virtual reality software, delivered through the "DR.VR" (TM) device.

Primary outcomes

  1. Data on the use of virtual reality for managing pain, from the perspective of people living with advanced cancer who experience pain.

    Time frame: 15 months

  2. A pilot of the intervention, how it will be implemented, and how it is expected to work.

    Time frame: 15 months

  3. A user-tested virtual reality intervention with a manual for use, including guidelines for use in clinical settings and research priorities

    Time frame: 15 months

Sponsors and collaborators

Lead sponsor

University College, London

Other

Collaborators

  • Brighton and Sussex University Hospitals NHS Trust
  • Lancaster University
  • Velindre NHS Trust

Registry information

Official study title

Developing and Refining a Virtual Reality Intervention That Will Help to Manage Pain for People Living With Advanced Cancer

Acronym: VRcan

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Aug 2, 2024
Registry last updated
Dec 6, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.