Venous Thromboembolism (VTE) Prophylaxis With REGN7508 and REGN9933 in Adult and Adolescent Participants With a Peripherally Inserted Central Catheter (PICC)

Key Inclusion Criteria:

• Is undergoing PICC placement for Intravenous (IV) administration of clinically indicated medications, including chemotherapy, antibiotics, TPN, and/or other indications as described in the protocol
• Has Eastern Cooperative Oncology Group Performance (ECOG) Status ≤3 or equivalent functional status as described in the protocol
• Has International Normalization Ratio (INR) and aPTT values no more than 25% above the upper limit as described in the protocol
• Weighs at least 40 kg during the screening period

Key Exclusion Criteria:

• Has a history of prior venous thrombosis in the arm and/or ipsilateral thoracic central veins in which the PICC is to be placed
• Has acute leukemia, myelodysplastic syndrome, or primary and secondary myelofibrosis
• Has unresected luminal gastrointestinal (GI) (including esophageal) or unresected genitourinary (GU) malignancy
• Has current or history of known brain tumors or brain metastases
• Has any major cardiovascular event within approximately the past 30 days prior to study administration
• Pre-existing central venous catheter or indwelling spinal or epidural catheter during the screening period

Note: Other Protocol Defined Inclusion/ Exclusion Criteria Apply