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OpenTrials
Completed

NCT Number: NCT03209661

Vascular Effects of a Single Bout of Electronic Cigarette Use

Investigating the acute effects of a single use E-Cigarette upon vascular health.

Completed

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Key information

Conditions

Arterial Stiffness

Age range

20 year–30 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

Cardiovascular Aging Research Lab at UT Austin

Austin, Texas, 78712, United States

About this study

Subjects will inhale e-cigarettes of 5.4%, 0%, and sham menthol inhaler to determine the effects upon to measures of vascular health. These measures will include Cardio-Ankle Vascular Index and Flow Mediated Dilation.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Apparently healthy, with no cardiovascular or metabolic diseases. Additionally, is not a frequent smoker of any kind.

Exclusion criteria

  • Cardiovascular or Metabolic Diseases and/or regular smoker.

Treatment and study plan

E-cigarette

Drug

E-Cigarette containing 5.4% nicotine will be administered to determine the effects on vascular function.

Other names: Nicotine 5.4%

Nicotine 0%

Drug

E-Cigarette containing 0% nicotine will be administered to determine the effects on vascular function.

Other names: Placebo

Menthol Inhalant Product

Drug

Menthol inhaler will be administered to determine the effects on vascular function.

Other names: Placebo

Primary outcomes

  1. Changes in arterial stiffness and endothelial function with e-cigarette use.

    Time frame: Immediately Post, 1 hour, and 2 hour.

    Arterial stiffness and endothelial function are two of the subclinical markers of vascular dysfunction

Sponsors and collaborators

Lead sponsor

University of Texas at Austin

Other

Registry information

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Jul 6, 2017
Registry last updated
Oct 11, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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