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Recruiting

NCT Number: NCT03704207

Utility of PCD Diagnostics to Improve Clinical Care

This is a study evaluating the utility of current Primary Ciliary Dyskinesia (PCD) diagnostic tests, including nasal nitric oxide testing.

Recruiting

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Key information

Conditions

Primary Ciliary Dyskinesia Abnormalities, Multiple Ciliary Motility Disorders Ciliopathies Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Genetic Diseases, Inborn Otorhinolaryngologic Diseases Respiratory Tract Diseases

Age range

1 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Vanderbilt Children's hospital

Nashville, Tennessee, 37232, United States

Location status: Recruiting

Location contact

Michael O'Connor, MD

CONTACT

About this study

This study is a prospective data collection of individuals referred to the investigators clinical center for considerations of PCD. Participants sign informed consent to have clinical information entered into a secure electronic database. As part of this study, participants may have nasal nitric oxide (nNO) testing performed. nNO testing is a research procedure, but it is a test with growing utility for making a diagnosis of PCD when performed in the right clinical setting.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Referred to center for PCD diagnosis considerations
  • Ability to perform study procedures
  • Age greater than 2 years of age

Exclusion criteria

  • Age less than 2 years of age Inability to perform informed consent

Treatment and study plan

nNO testing

Other

Collection of already performed clinical data and nNO testing

Primary outcomes

  1. frequency of nNO tests performed

    Time frame: 3 years

    number of tests

  2. Frequency of genetic tests performed

    Time frame: 3 years

    number of tests

Study contacts

Contact information is provided by the study sponsor or research team.

Michael O'Connor, MD

CONTACT

[email protected]

615.343.7617

Sponsors and collaborators

Lead sponsor

Vanderbilt University Medical Center

Other

Registry information

Important dates

Study start
2017
Primary completion
2028
Study completion
2028
First posted
Oct 12, 2018
Registry last updated
Jul 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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