Utility and Cost-effectiveness of Microscopic Examination of the Neck Dissection.

Most patients with cancer of the head and neck are offered surgical resection of the primary tumor. In order to determine how the tumor will eventually behave, along with the resection of the primary tumor, lymph nodes present in the neck are also dissected. Different institutes have different protocol on handling of the specimen that is received by the pathology labs after dissection of the neck. The investigators intend to analyze the protocol that they use to evaluate the neck dissection specimen.

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Key information

Conditions

Metastasis Neoplasm Metastasis Neoplasms Neoplastic Processes Pathologic Processes Pathological Conditions, Signs and Symptoms

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Mississippi Medical Center

Jackson, Mississippi, 39216, United States

About this study

This will be a retrospective study. All neck dissections received in the histology laboratory from Jan 2013 to December 2016 will be retrieved from the histopathology files by conducting a search through CoPath. The glass slides of all the neck dissections that fit the study criterion will be retrieved from the archives. The glass slides will be reviewed by the pathologist.

At the time of review number of lymph nodes identified microscopically, presence or absence of metastasis and if the Lymph Nodes (LN) were palpable or not palpable will be documented. The data will be analyzed to see if the submission of extra fat yielded any additional positive lymph nodes or microscopic deposits. The cost analysis for additional slides will be also done.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Neck dissection (unilateral and/or bilateral)
Primary squamous cell carcinoma of head and neck

Exclusion criteria

Any neck dissection performed outside UMMC and case received as a consult.

Treatment and study plan

additional soft tissue in neck dissections

Other

Evaluation of submission of additional soft tissue in neck dissections for head and neck squamous cell carcinomas

Primary outcomes

Number of additional lymph nodes obtained with additional sampling of soft tissue

Time frame: 3 years

Number of additional lymph nodes obtained with additional sampling of soft tissue

Sponsors and collaborators

Lead sponsor

University of Mississippi Medical Center

Other

Registry information

Official study title

Utility and Cost-effectiveness of Microscopic Examination of the Neck Dissection Specimen in Its Entirety.

Important dates

Study start: 2013
Primary completion: 2016
Study completion: 2017
First posted: Aug 2, 2017
Registry last updated: Feb 20, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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