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Completed

NCT Number: NCT04298294

Using of Injectable Platelet Rich Fibrin on Filling the Gap of Immediate Dental Implant

The effect of using of i-PRF (injectable platelet rich fibrin) on filling the gap of immediate dental implant in the esthetic zone

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Key information

Age range

20 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Bassant Mohye

Cairo, 11724, Egypt

About this study

Grouping the samples: (sixteen patients was recruited from the outpatient clinic of Oral Medicine, Periodontology, Diagnosis and Radiology Department, Faculty of Dentistry, Ain Shams University).

The sixteen patients assigned to group 1 or group 2 will be randomly allocated using flip of a coin into one of the 2 treatment modalities.

Primary objective:

Radiograhic evaluation of the effect of i-PRF on filling the buccal gap distance between the immediately placed dental implant and the surrounding bone.

Secondary objective:

Esthetic evaluation of the effect of i-PRF on the soft tissue around immediately placed dental implant.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy adult patient.
  • Age from 20-50 years old
  • Patients must be free of any systemic disease which could influence the surgical procedure.
  • Tooth involved in the esthetic zone.
  • Sufficient hard and soft tissue volume in vertical and buccolingual 6. Natural teeth adjacent to the involved tooth were required to be free from infection.
  • Controlled oral hygiene.
  • Indication for tooth extraction included;
  • Endodontic failures
  • Untreatable caries> Non- restorable teeth
  • Vertical root fracture
  • Remaining roots
  • The decision to proceed with the implant placement was made after tooth extraction and probing of the extraction socket which revealed:
  • The presence of intact facial bone.
  • Compliance with all requirements in the study and signing the informed consent.

Exclusion criteria

  • Patient had surgeries in the same site during the last 6 months prior to the surgery.
  • Severe vertical bone loss (socket type lll or type lV).
  • Presence of acute dento-alveolar infection or periodontal affected of involved tooth.
  • Pregnant and lactating females.
  • Smokers.

Treatment and study plan

Injectable Platelet Rich Fibrin

Other

biologic activator

Primary outcomes

  1. Radiograhic evaluation of the effect of i-PRF on filling the buccal gap distance between the immediately placed dental implant and the surrounding bone.

    Time frame: 6 months follow up

    density, vertical and horizontal assessment of labial plate

  2. Radiographic analysis

    Time frame: 6 months follow up

    vertical assessment of labial plate

  3. Radiographic analysis

    Time frame: 6 months follow up

    density of labial plate

Secondary outcomes

  1. Esthetic evaluation of the effect of i-PRF on the soft tissue around immediately placed dental implant

    Time frame: 6 months follow up

    pink esthetic score

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

The Effect of Using of Injectable Platelet Rich Fibrin on Filling the Gap of Immediate Dental Implant in the Esthetic Zone

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
Mar 6, 2020
Registry last updated
Mar 6, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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