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Completed

NCT Number: NCT00871676

Use of Chewing Gum to Facilitate Appetite Control and Weight Loss

This purpose of this study was to test the use of chewing gum as an adjunct to lifestyle modification to facilitate appetite control and weight loss in overweight and obese individuals.

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Key information

Conditions

Overweight Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

21 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Pennsylvania School of Medicine

Philadelphia, Pennsylvania, 19104, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 21-75 years of age
  • Body Mass Index of 25-45 inclusive

Exclusion criteria

  • major medical psychiatric conditions
  • medications know to effect weight
  • full or partial dentures
  • 18 or fewer teeth
  • regular gum chewing (≥ 2 pieces/day)
  • use of any tobacco product
  • sensitivity to the following ingredients (mint, magnolia bark, eggs, or English Muffins)
  • history of PKU
  • sensitivity or allergy to aspartame
  • current/history of alcohol abuse or addiction (within 5 year)
  • recreational drug use
  • recent significant weight change (+/- 5% in previous 6 months)
  • currently pregnant or nursing and willingness not to get pregnant during course of study
  • participation in any other research studies
  • proximity to clinic (within one hour)
  • access to reliable transportation

Treatment and study plan

Lifestyle Modification

Behavioral

16 weekly followed by 8 monthly group behavioral weight loss sessions.

Other names: Behavior modification, Behavioral weight loss

Lifestyle modification plus gum

Behavioral

16 weekly followed by 8 monthly group behavioral weight loss sessions. Subjects were also given gum along with instructions for times and occasions to chew with the aim of facilitating weight loss and appetite control.

Other names: Behavior modification, Behavioral weight loss

Primary outcomes

  1. Weight loss

    Time frame: Week 16 and 52

Secondary outcomes

  1. Appetite control

    Time frame: Weeks 4, 8, 12, 16 and 52

Sponsors and collaborators

Lead sponsor

University of Pennsylvania

Other

Collaborators

  • St. Luke's-Roosevelt Hospital Center

Registry information

Official study title

Use of Chewing Gum to Facilitate Appetite Control and Weight Loss in Overweight Individuals Treated by Lifestyle Modification

Important dates

Study start
2006
Primary completion
2009
Study completion
2009
First posted
Mar 30, 2009
Registry last updated
Aug 17, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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