Use of Atropine in Tredmill Stress Testing

The aim of this study is to evaluate the Safety and feasibility of atropine added during treadmill stress testing in patients with chronotropic incompetence or poor exercise capacity.

Our hypothesis is that we can increase heart rate by using atropin in these patients, so we will achieve more conclusive results.

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Key information

Conditions

Chest Pain Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Phase 3

Primary location

Heart Institute, Ha'Emek Medical Center

Afula, 18100, Israel

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with chest pain without evidence of ischemia eligible for exercise test.
Age> 18 years old

Exclusion criteria

Absolute:

Patients with LBBB
Unstable Angina
Recent Myocardial Infarction
Un controlled Arrythmia
Congestive heart faliure
Severe symptomatic valvular heart disease
Acute Pulmonary Embolism
Acute perimyocarditis
Acute aortic dissection

Relative:

Lt main stenosis
Severe hypertention (Systolic> 200 mmHg; Diastolic > 100 mmHg)
Cardiomyopathy
Obstructiove abnormalities
Psychiatric disorders
High degree AV Block

Treatment and study plan

Atropine

Drug

I.V Atropine 0.5mg up to 2 mg

Primary outcomes

1- To characterize patients who can't achieve target heart rate at treadmill exercise test.2- To evaluate atropine added during treadmill stress testing in order to increase heart rate and achieave conclusive test.

Time frame: 1 yaer

Sponsors and collaborators

Lead sponsor

HaEmek Medical Center, Israel

Other

Registry information

Official study title

Safety and Feasibility of Atropine Added During Treadmill Stress Testing in Patients With Chronotropic Incompetence or Poor Exercise Capacity.

Important dates

Study start: 2007
Primary completion: 2009
Study completion: 2009
First posted: Feb 25, 2008
Registry last updated: Jul 27, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed