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Completed

NCT Number: NCT07424417

Upper Extremity Position and Intraocular Pressure During Spinal Anesthesia: A Randomized Controlled Trial

This prospective randomized controlled trial evaluated the effect of two upper extremity positions on intraocular pressure (IOP) in adult patients undergoing surgery under spinal anesthesia. Participants were randomly assigned to either an arms-at-sides position or a hands-on-chest position. IOP was measured in the right eye using an Icare ic200 rebound tonometer at predefined perioperative time points. Hemodynamic parameters, including mean arterial pressure, heart rate, and oxygen saturation, were also recorded. The primary outcome was the change in IOP from baseline to 30 minutes between the two upper extremity position groups.

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Elazığ Fethi Sekin City Hospital

Elâzığ, Outside of the US, 23200, Turkey (Türkiye)

About this study

Intraocular pressure (IOP) may be influenced by systemic hemodynamics, venous return, episcleral venous pressure, and patient positioning. Although the effects of head and body position on IOP have been investigated, the impact of upper extremity positioning during spinal anesthesia has not been clearly established.

This prospective randomized controlled trial was conducted at Elazig Fethi Sekin City Hospital. Adult patients scheduled for elective surgery under spinal anesthesia were enrolled. After written informed consent, participants were randomly assigned to one of two upper extremity positions: arms positioned alongside the body or hands positioned on the chest.

IOP was measured in the right eye using an Icare ic200 rebound tonometer. Measurements were obtained at baseline, 15 minutes, and 30 minutes after spinal anesthesia and positioning. Head and neck position was maintained neutral throughout the measurement period.

Hemodynamic parameters, including mean arterial pressure, heart rate, and peripheral oxygen saturation, were recorded simultaneously. The primary outcome was the change in IOP from baseline to 30 minutes between the two study groups. Secondary outcomes included IOP change at 15 minutes and perioperative hemodynamic changes.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 18 and 80 years
  • ASA physical status I-III
  • Scheduled for elective open inguinal hernia repair under spinal anesthesia
  • Ability to undergo intraocular pressure measurement
  • Provision of written informed consent

Exclusion criteria

  • History of glaucoma or ocular hypertension
  • Previous ocular surgery or ocular trauma
  • Active ocular disease or infection
  • Contraindication to spinal anesthesia
  • Inability to cooperate with intraocular pressure measurements
  • Refusal to participate

Treatment and study plan

Upper Extremity Positioning

Other

Participants were assigned to one of two upper extremity positions during spinal anesthesia: arms positioned alongside the body or hands positioned over the chest.

Primary outcomes

  1. Change in Intraocular Pressure From Baseline to 30 Minutes

    Time frame: Baseline and 30 minutes after spinal anesthesia and upper extremity positioning

    Intraocular pressure was measured in the right eye using an Icare ic200 rebound tonometer. The primary outcome was the change in intraocular pressure from baseline to 30 minutes after spinal anesthesia and upper extremity positioning between the two study groups.

Secondary outcomes

  1. Change in Intraocular Pressure From Baseline to 15 Minutes

    Time frame: Baseline and 15 minutes after spinal anesthesia and upper extremity positioning

    Intraocular pressure was measured in the right eye using an Icare ic200 rebound tonometer. This secondary outcome was the change in intraocular pressure from baseline to 15 minutes after spinal anesthesia and upper extremity positioning between the two study groups.

  2. Mean Arterial Pressure

    Time frame: Baseline, 15 minutes, and 30 minutes after spinal anesthesia and upper extremity positioning

    Mean arterial pressure was recorded simultaneously with intraocular pressure measurements and evaluated between the two study groups.

Sponsors and collaborators

Lead sponsor

Elazıg Fethi Sekin Sehir Hastanesi

Other

Registry information

Acronym: UEP-IOP

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Feb 20, 2026
Registry last updated
May 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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