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Completed

NCT Number: NCT06993961

Ultrasound Measurement of Optic Nerve Sheath Diameter as Non-Invasive Detector of Raised Intracranial Pressure in Adult Traumatic and Non-Traumatic Neurocritical Patients in ICU

This study aimed to assess the role of ultrasound as a non-invasive method (bedside) to measure the rise of intracranial pressure by measuring the optic nerve sheath diameter in traumatic and nontraumatic neurocritical patients.

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Key information

Conditions

Ultrasound Intensive Care Unit Intracranial Pressure Neurocritical Non-invasive Optic Nerve Sheath Diameter

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ain Shams University

Cairo, 11591, Egypt

About this study

Measurement of intracranial pressure (ICP) is crucial in the management of many neurological conditions. However, due to the invasiveness, high cost, and required expertise of available ICP monitoring techniques, many patients who could benefit from it do not receive it. As a result, a substantial effort has been made to explore and develop novel non-invasive ICP monitoring techniques to improve the overall clinical care of patients suffering from ICP disorders.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age >18 years old.
  • Both sexes.
  • Patients with suspected high intracranial pressure.

Exclusion criteria

  • Cases suffering from eye disease or optic nerve problems (Glaucoma, optic Nerve Tumor, Neuritis, Orbital Fracture).
  • Patients suffering from mental illness render them incapable of communication & cooperation (For Example: Dementia and irritability).
  • Any previous intensive care surgeries & hyperthyroidism (due to exophthalmos)

Treatment and study plan

Ultrasound

Device

Ultrasound (US) measurement of optic nerve sheath diameter (ONSD) was performed.

Primary outcomes

  1. Intracranial Pressure

    Time frame: 24 hours post-procedure

    Non-invasive bedside intracranial pressure (ICP) assessment via ultrasound (US) measurement of optic nerve sheath diameter (ONSD).

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
May 29, 2025
Registry last updated
May 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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