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NCT Number: NCT07352189

Ultrasound-Guided Versus Laparoscopy-Guided Transversus Abdominis Plane Block for Postoperative Analgesia

This prospective, randomized, double-blind study aimed to compare the effects of ultrasound-guided versus laparoscopy-guided transversus abdominis plane(TAP) block on postoperative analgesia in patients undergoing laparoscopic upper abdominal surgery under general anesthesia. Postoperative pain scores, analgesic consumption and recovery parameters were evaluated during the first 24 hours after surgery.

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Key information

Conditions

Postoperative Pain Management Agnosia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Perceptual Disorders Postoperative Complications Signs and Symptoms

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Maltepe University Faculty of Medicine Hospital

Istanbul, 34000, Turkey (Türkiye)

About this study

Patients aged 18-70 years with ASA physical status I-III who were scheduled for laparoscopic upper abdominal surgery under general anesthesia were included in the study. After induction of anesthesia, patients were randomly assigned to one of two group, bilateral subcostal transversus abdominis plane block was performed under ultrasound-guidance using a local anesthetic mixture before extubation. In the laparoscopy-guided group, bilateral subcostal transversus abdominis plane block was performed under laparoscopic guidance using the same local anesthetic mixture before abdominal closure. Postoperative pain intensity was assessed by using the Numeric Rating Scale (NRS). Total opioid consumption, time to first analgesic requirement, paracetamol consumption, postoperative nausea and vomiting, length of hospital stay, time to ambulation and time to gastrointestinal recovery were recorded during the first 24 hours after surgery. Complications related to the TAP block were also evaluated.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 18-70 yeras
  • ASA physical status I-III
  • Scheduled for laparoscopic upper abdominal surgery
  • Provided written informed consent

Exclusion criteria

  • Patient refusal
  • Allergy to local anesthetics
  • Coagulopathy
  • Infection at the injection site
  • Severe systemic disease
  • ASA physical status IV-V

Treatment and study plan

Ultrasound-guided Transversus Abdominis Plane (US-TAP) Block

Procedure

Bilateral ultrasound-guided subcostal transversus abdominis plane block performed prior to extubation using a total of 40 mL local anesthetic solution (30 mL0.25% bupivacaine and 10 ml of 1% lidocaine).

Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) Block

Procedure

Bilateral laparoscopy-guided transversus abdominis plane block performed prior to extubation using a total of 40 mL local anesthetic solution (30 mL 0.25% bupivacaine and 10 ml of 1% lidocaine).

Primary outcomes

  1. Postoperative pain score (NRS)

    Time frame: First 24 hours postoperatively

    Postoperative pain intensity measured using the Numeric Rating Scale (NRS), a 0-10 scale where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicates worse pain.

Sponsors and collaborators

Lead sponsor

Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital

Other

Collaborators

  • Maltepe University

Registry information

Official study title

Comparison of the Efficacy of Ultrasound-Guided and Laparoscopy-Guided Transversus Abdominis Plane(TAP) Block on Postoperative Analgesia in Patients Undergoing Laparoscopic Upper Abdominal Surgery

Acronym: US-LTAP

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Jan 20, 2026
Registry last updated
Jan 21, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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