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NCT Number: NCT07081867

Comparison of Sacral Erector Spinae Plane Block and Supra-Inguinal Fascia Iliaca Block for Analgesia After Hip Fracture Surgery

This study compares the postoperative analgesic effectiveness of Sacral Erector Spinae Plane Block (SESPB) and Supra-Inguinal Fascia Iliaca Block (SIFIB) in patients undergoing hip fracture surgery. Both techniques are regional anesthesia methods aiming to reduce postoperative pain and opioid consumption. The study evaluates pain scores, opioid requirements, mobilization times, and hospital discharge times to determine which block provides more effective pain management in different postoperative periods.

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Key information

About this study

Hip fractures are common injuries among elderly patients, often resulting in high rates of morbidity and mortality. Effective postoperative pain management plays a critical role in reducing complications such as delayed mobilization, deep vein thrombosis, pneumonia, and prolonged hospitalization.

Regional anesthesia techniques, including Sacral Erector Spinae Plane Block (SESPB) and Supra-Inguinal Fascia Iliaca Block (SIFIB), have gained popularity as part of multimodal analgesia strategies that aim to minimize opioid use and improve postoperative comfort. However, there is limited evidence comparing these two techniques directly.

In this prospective observational study, patients aged 65 and older undergoing hip fracture surgery under spinal anesthesia were included. After obtaining informed consent, patients received either SESPB or SIFIB for postoperative analgesia in addition to the standard anesthetic protocol.

Pain levels were assessed using the Visual Analog Scale (VAS) at 1, 6, 12, and 24 hours after surgery. Additional data such as total opioid consumption within 24 hours, time to first analgesic requirement, mobilization time, and length of hospital stay were recorded.

The results demonstrated that patients who received SIFIB had significantly lower pain scores in the early postoperative period (1st hour), while patients who received SESPB experienced better pain relief in the late postoperative period (24th hour). No significant differences were observed between the groups in terms of total opioid consumption, mobilization time, or hospital stay duration. No complications related to the block procedures were reported.

This study suggests that both SESPB and SIFIB are safe and effective regional anesthesia techniques for postoperative pain management in hip fracture surgeries. The selection between these blocks may be based on the desired onset and duration of analgesia, with SIFIB providing superior early pain control and SESPB offering more prolonged analgesic effects.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 65 years and older
  • Patients undergoing surgery for hip fractures under spinal anesthesia
  • Patients who are oriented and cooperative
  • Patients who have signed an informed consent form

Exclusion criteria

  • Patients with contraindications for spinal anesthesia
  • Patients with Alzheimer's disease or dementia, and those who are non-oriented or non-cooperative
  • Patients with major organ failure (such as heart, liver, or kidney failure)
  • Patients who decline to participate in the study
  • Patients classified as American Society of Anesthesiologists (ASA) Physical Status IV or higher
  • Patients with pathological fractures or bone metastasis

Treatment and study plan

Supra-inguinal Fascia Iliaca Block (SIFIB)

Procedure

Ultrasound-guided injection of 40 mL of 0.25% bupivacaine between the iliacus muscle and fascia iliaca via a supra-inguinal approach, performed preoperatively for postoperative analgesia in patients undergoing hip fracture surgery under spinal anesthesia.

Sacral Erector Spinae Plane Block (SESPB)

Procedure

Ultrasound-guided injection of 40 mL of 0.25% bupivacaine into the fascial plane deep to the erector spinae muscle at the sacral level (S2), performed preoperatively for postoperative analgesia in patients undergoing hip fracture surgery under spinal anesthesia.

Primary outcomes

  1. Postoperative Pain Scores

    Time frame: At 1 hour, 6 hours, 12 hours, and 24 hours postoperatively.

    Pain intensity measured using the Visual Analog Scale (VAS), ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst pain imaginable. Pain scores will be recorded at specific postoperative time points: 1st, 6th, 12th, and 24th hours.

  2. Time to First Postoperative Analgesic Requirement

    Time frame: Up to 48 hours postoperatively.

    Time interval from end of surgery to the first request for analgesia.

  3. Total Postoperative Opioid Consumption

    Time frame: A week

    The total amount of opioids required by patients during the postoperative period.

  4. Time to First Mobilization

    Time frame: From the end of surgery until first mobilization, typically within 24 to 48 hours postoperatively

    The time until patients' first mobilization (walking or standing) after surgery.

Secondary outcomes

  1. Length of Hospital Stay

    Time frame: Up to 14 days postoperatively.

    Duration from the day of surgery to the day of hospital discharge, measured in calendar days.

  2. Block-Related Complications

    Time frame: A week

    Possible complications following Sacral Erector Spinae Plane Block (SESPB) and Supra-Inguinal Fascia Iliaca Block (SIFIB), such as nerve injury, infection, hematoma, etc.

Sponsors and collaborators

Lead sponsor

Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization

Other

Registry information

Official study title

Comparison of Postoperative Analgesic Efficacy of Preoperatively Performed Sacral Erector Spinae Plane Block and Supra-Inguinal Fascia Iliaca Block in Patients Undergoing Surgery for Hip Fracture

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 23, 2025
Registry last updated
Jan 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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