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NCT Number: NCT07701720

Ultrasound Guidance vs. Landmark Technique for Catheter Malposition in IJV Catheterization

Central venous catheterization (CVC) via the internal jugular vein (IJV) is a fundamental procedure in anesthesia and intensive care for hemodynamic monitoring, fluid resuscitation, and vasoactive drug administration. While modern clinical guidelines strongly advocate for ultrasound (USG) guidance, the traditional anatomical landmark technique remains widely utilized due to equipment availability or clinician habits. Proper positioning of the catheter tip is critical to prevent severe long-term complications; however, comparative data regarding catheter tip malposition between these two routine techniques-especially when confirmed by postprocedural bedside chest X-ray-require further prospective evaluation. Objective:

The primary objective of this prospective observational study is to compare ultrasound-guided versus landmark techniques for internal jugular vein catheterization with respect to catheter tip malposition, as determined by postprocedural bedside chest X-ray. Secondary objectives include the evaluation of the number of needle redirections, first-attempt success rate, total procedure time, and the incidence of mechanical complications (such as accidental arterial puncture or hematoma formation)

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Key information

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 18-75 undergoing surgery requiring central venous (internal jugular) catheterization

Exclusion criteria

  • Refusal to participate
  • age <18 or >75
  • emergency surgery
  • coagulopathy
  • infection, prior surgery, or prior cannulation at the insertion site
  • allergy to ultrasound gel

Treatment and study plan

Ultrasound-Guided Technique

Procedure

Internal jugular vein catheterization performed with real-time ultrasound visualization of the vein to guide needle insertion.

landmark technique

Procedure

Internal jugular vein catheterization performed using external anatomical landmarks without real-time ultrasound guidance.

Primary outcomes

  1. Incidence of catheter tip malposition

    Time frame: Assessed on postoperative bedside chest X-ray, immediately following the procedure

Secondary outcomes

  1. Incidence of Procedural Mechanical Complications

    Time frame: During the procedure and up to 24 hours post-operatively.

    The occurrence and rate of immediate mechanical complications directly related to the intervention, specifically tracking accidental carotid arterial punctures and hematoma formations.

Study contacts

Contact information is provided by the study sponsor or research team.

Fikret Salık Assoc. Prof. Dr.

CONTACT

[email protected]

0507 621 41 25

Sponsors and collaborators

Lead sponsor

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Other

Registry information

Official study title

The Effect of Ultrasound Guidance Versus Landmark Technique on Catheter Malposition in Internal Jugular Vein Catheterization

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jul 14, 2026
Registry last updated
Jul 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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