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Completed

NCT Number: NCT07057869

Ultrasound Duration Effects on Knee Osteoarthritis Pain and Function

This study aims to compare the effects of different ultrasound treatment durations on pain and physical function in patients with knee osteoarthritis. Sixty sedentary volunteers aged 18-85 with diagnosed knee osteoarthritis will be randomly assigned to three groups receiving ultrasound therapy for 5, 10, or 15 minutes, respectively, alongside conventional treatment. Pain and physical function will be assessed using the Visual Analog Scale (VAS), WOMAC Osteoarthritis Index, and 2-minute walk test at baseline and after 4 weeks of treatment. The results will help determine the optimal ultrasound treatment duration for improving symptoms in knee osteoarthritis patients.

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Key information

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

KTO Karatay Üniversitesi

Konya, 42080, Turkey (Türkiye)

About this study

This clinical trial investigates the effects of different ultrasound therapy durations on pain relief and physical function improvement in patients with knee osteoarthritis. Sixty sedentary individuals aged 18 to 85 years diagnosed with knee osteoarthritis will be enrolled and randomly assigned to three groups receiving ultrasound treatment for 5, 10, or 15 minutes, respectively, alongside conventional therapy (such as hot packs, TENS, etc.).

Ultrasound therapy will be applied by a qualified physiotherapist at 1 W/cm² intensity and 1 MHz frequency in pulsed mode, for four weeks. Evaluations will be conducted at baseline and after treatment completion, using the Visual Analog Scale (VAS) for pain assessment, WOMAC Osteoarthritis Index for physical function, and a 2-minute walk test to measure walking performance.

This study aims to provide scientific evidence on the optimal ultrasound treatment duration for knee osteoarthritis, contributing to improved rehabilitation protocols. The findings will be prepared for publication in an international peer-reviewed journal.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Individuals aged between 18 and 85 years Diagnosed with knee osteoarthritis Recommended for ultrasound therapy as part of routine physical therapy Willing to participate voluntarily and provide written informed consent

Exclusion criteria

History of acute knee trauma Individuals with contraindications to ultrasound therapy

Treatment and study plan

5-minute Ultrasound Group

Procedure

Pulsed ultrasound therapy applied at 1 W/cm² intensity and 1 MHz frequency for 5 minutes per session, 4 weeks duration.

10-minute Ultrasound Group

Procedure

Pulsed ultrasound therapy applied at 1 W/cm² intensity and 1 MHz frequency for 10 minutes per session, 4 weeks duration.

15-minute Ultrasound Group

Procedure

Pulsed ultrasound therapy applied at 1 W/cm² intensity and 1 MHz frequency for 15 minutes per session, 4 weeks duration.

Primary outcomes

  1. Pain Intensity (VAS)

    Time frame: Baseline, 4 weeks

    Assessment of knee pain intensity using the Visual Analog Scale (VAS) at baseline and after 4 weeks of treatment.

  2. Physical Function (WOMAC)

    Time frame: Baseline, 4 weeks

    Evaluation of physical function and stiffness using the WOMAC index at baseline and after 4 weeks of treatment.

Secondary outcomes

  1. Walking Distance (2-Min Walk)

    Time frame: Baseline, 4 weeks

    Distance covered in 2 minutes walking test at baseline and after 4 weeks of treatment.

Sponsors and collaborators

Lead sponsor

KTO Karatay University

Other

Registry information

Official study title

Comparison of the Effects of Different Ultrasound Treatment Durations on Pain and Physical Function in Patients With Knee Osteoarthritis

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 10, 2025
Registry last updated
Jul 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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