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NCT Number: NCT07418775

Tumor Genomics, Individual Risk Factors, and External Drivers of Health on Health Outcomes for Patients With Meningioma

Meningiomas are the most common primary brain tumor, and some groups are diagnosed with higher-grade tumors and have clinically worse outcomes. This study investigates social determinants of health and individual risk factors that may be associated with meningioma.

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Key information

Conditions

Meningioma of Brain Brain Diseases Brain Neoplasms Brain Tumor Central Nervous System Diseases Central Nervous System Neoplasms Meningeal Neoplasms Meningioma Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Nerve Tissue Neoplasms, Vascular Tissue Nervous System Diseases Nervous System Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

PRIMARY OBJECTIVES:

I. To assess prevalence and distribution of social and structural determinants of health (SSDH) among meningioma patients.

II. To assess disparities in SSDH among meningioma patients of different races.

OUTLINE: This is an observational study.

Participants will complete a survey and have their medical records reviewed.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults ≥18 years of age
  • Able to speak and read English
  • Diagnosed with a meningioma

Exclusion criteria

  • Active psychiatric issues (suicidality, active psychosis, grave disability, etc.)
  • Inability to consent secondary to severe neurologic deficit or psychiatric distress
  • Inability to complete survey secondary to severe neurologic deficit or psychiatric distress

Treatment and study plan

Questionnaire

Behavioral

A questionnaire will be administered in person or online

Medical Record Review

Other

Medical records will be reviewed for study specific data collection

Primary outcomes

  1. Identifying potential social and structural determinants of health (SSDH)

    Time frame: Up to 5 years

    The prevalence of SSDH factors such as race and ethnicity, birthplace, relationship status, sexual orientation/gender identity, education level, socio-economic status, access to care, reproductive/menstrual history, health factors and medication use, chemical and radiation exposure, smoking history, and perceived stress for participants with meningioma will be analyzed using multilevel logistic and linear models accounting for geographical clustering.

  2. Distribution of social and structural determinants of health

    Time frame: Up to 5 years

    The distribution of SSDH factors across racial groups will be analyzed using multilevel logistic and linear models accounting for geographical clustering.

  3. Identify disparities in social and structural determinants of health (SSDH)

    Time frame: Up to 5 years

    Disparities of SSDH factors across racial groups will be analyzed using multilevel logistic and linear models accounting for geographical clustering.

Study contacts

Contact information is provided by the study sponsor or research team.

Zora Arum

CONTACT

[email protected]

877-827-3222

Sponsors and collaborators

Lead sponsor

University of California, San Francisco

Other

Collaborators

  • National Cancer Institute (NCI)

Registry information

Official study title

An Investigation of Tumor Genomics, Individual Risk Factors, and External Drivers of Health to Improve Health Outcomes for Patients With Meningioma

Important dates

Study start
2026
Primary completion
2031
Study completion
2032
First posted
Feb 18, 2026
Registry last updated
May 19, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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