Percutaneous coronary intervention of coronary chronic total occlusion
ProcedureCoronary CTO was identified by coronary angiography, and its revascularization was attempted by either antegrade, retrograde or both approach.
Other names: PCI to CTO
NCT Number: NCT06917378
Coronary chronic total occlusions (CTO) present a significant challenge in the field of interventional cardiology. These complex lesions, characterized by complete blockage of a coronary artery for a prolonged duration, often require specialized techniques and strategies to achieve successful revascularization.
Interested in participating?
Request Info20 year–120 year
All sexes
Observational
Chang Gung Memorial Hospital, New Taipei City, Taiwan
Using this consortium, we will establish a multicenter cohort to evaluate the clinical parameters, angiographic characteristics, interventional techniques, and clinical outcomes involved in coronary CTO intervention. 3 subprojects are listed here.
Subproject 1 intends to develop a novel algorithm integrating antegrade and retrograde scoring system to optimize the CTO intervention and determine the optimal timing for primary retrograde approach. Current algorithm for CTO intervention.
Subproject 2 aims to examine the strategies and outcomes of CTO involving bifurcations. Bifurcation CTO lesions present unique challenges due to their complex anatomy. Opening of the main vessel while preserving important branches is crucial for ensuring favorable long-term clinical prognosis. This subproject will investigate different strategies and devices employed in bifurcation CTO PCI to assess their efficacy and safety outcomes.
Subproject 3 investigates the treatment strategies for right coronary artery (RCA) CTOs with concomitant left main disease, which present a unique and intricate scenario, requiring careful consideration of revascularization strategies.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Nil
Coronary CTO was identified by coronary angiography, and its revascularization was attempted by either antegrade, retrograde or both approach.
Other names: PCI to CTO
Time frame: 1 day
Successful CTO recanalization with <20% residual stenosis within the treated segment and restoration of Thrombolysis in Myocardial Infarction grade 3 antegrade flow, without side branch loss
Time frame: 1 day
retrograde guidewire crossing the CC to reach the distal cap of CTO segment.
Time frame: 5 years
Death, CV death, myocardial infarction, stroke, repeat revascularization
Time frame: 1 day
Confirmed by
Time frame: 1 day
Periprocedural myocardial infarction, vessel perforation, stroke, urgent or emergent revascularization
Contact information is provided by the study sponsor or research team.
National Taiwan University Hospital
Other
The Multicenter Study to Evaluate Clinical and Angiographic Factors in Patients With Coronary Artery Chronic Total Occlusion in Taiwan
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