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NCT Number: NCT07451860

Chronic Total Occlusion and Triglyceride-Glucose Index

We retrospectively analyzed 200 CAD patients undergoing coronary angiography between 2026-2027. Patients were grouped by CTO presence. Clinical and laboratory parameters were compared, and logistic regression was performed to identify independent predictors.

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Key information

Conditions

CAD - Coronary Artery Disease Arterial Occlusive Diseases Arteriosclerosis Cardiovascular Diseases Chronic Total Occlusion (CTO) Coronary Artery Disease Coronary Disease Heart Diseases Myocardial Ischemia Triglycerid Glucose Index Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults ≥18 years of age, patients undergoing coronary angiography, non-obese individuals

Exclusion criteria

  • Patients <18 years of age, history of atrial fibrillation, pacemaker implantation, asthma, pulmonary hypertension, pregnancy, anemia, malignancy, rheumatoid arthritis, or peripheral artery disease, obesity (BMI >30 kg/m²), inaccessible patient records

Treatment and study plan

triglyceride-glucose (TyG) index was calculated from routinely obtained blood samples using the formula: Triglyceride (mg/dL) × Glucose (mg/dL) / 2.

Diagnostic Test

As no previous studies have demonstrated the predictive value of the TyG index for chronic total occlusion (CTO), the present investigation provides a novel contribution to the literature. We hypothesize that the triglyceride-glucose (TyG) index will be significantly higher in patients with chronic total occlusion (CTO) compared to those without CTO.

Primary outcomes

  1. The primary outcome measure will be the difference in the triglyceride-glucose (TyG) index between patients with chronic total occlusion (CTO) and those without CTO, assessed from routinely obtained blood samples.

    Time frame: 1 Year

Study contacts

Contact information is provided by the study sponsor or research team.

RUKİYE GÖNEN ÖZDEMİR

CONTACT

[email protected]

+905054503953

Sponsors and collaborators

Lead sponsor

Kırıkkale University

Other

Registry information

Official study title

The Role of the Triglyceride-Glucose Index in Determining the Risk of Chronic Total Occlusion in Coronary Artery Disease

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Mar 5, 2026
Registry last updated
Mar 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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