Treatment of Severe Male Infertility - Predictive Factors (Imaging)

Testes of men with non-obstructive azoospermia (NOA) are imaged using MRI to find potential differences depending on the outcome, ie. sperm recovery in consequent microdissection testicular sperm extraction (MD-TESE).

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Male Infertility Azoospermia Genital Diseases Genital Diseases, Male Infertility Infertility, Male Male Urogenital Diseases Urogenital Diseases

Age range

18 year–50 year

Sex eligibility

Male

Study type

Observational

Primary location

Dept of Obst and Gyn, Turku, Finland

About this study

Sperm recovery rate in non-obstructive azoospermia (NOA) men is 43% in Turku University Hospital, depending on the diagnosis leading to NOA. To date, there are no known parameters known to differentiate between successful and unsuccessful sperm recovery.

MRI is performed on men prior to the operation, and the objective is to compare the functional parameters assessed by magnetic resonance imaging between the group of men with positive and the men with negative sperm recovery in testicular microdissection sperm extraction (MD-TESE).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

non obstructive azospermia

Exclusion criteria

malignancy
contraindication for fertility treatment

Treatment and study plan

MRI

Diagnostic Test

Pelvis MRI

Primary outcomes

Functional difference in testicular MRI depending on MD-TESE outcome (=sperm recovery)

Time frame: Baseline/ pre-invention

ADC differences by diagnosis and outcome

Sponsors and collaborators

Lead sponsor

Turku University Hospital

Other Gov

Registry information

Acronym: TESE-MRI

Important dates

Study start: 2016
Primary completion: 2023
Study completion: 2023
First posted: Oct 13, 2016
Registry last updated: Nov 1, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed