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OpenTrials
Completed

NCT Number: NCT03737383

Treating Violence-related PTSD and Substance Risk in Low-income, Urban Adolescents

This project will provide initial feasibility and efficacy data for the implementation of Narrative Exposure Therapy (NET) to urban, at-risk youth. Posttraumatic stress and substance use outcomes, as well as participant responses to the intervention, will be examined.

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Key information

Age range

16 year–25 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University at Buffalo Department of Psychology

Buffalo, New York, 14260, United States

About this study

The goal of the proposed study is to gather preliminary feasibility and efficacy data for an innovative intervention (Narrative Exposure Therapy: NET) to promote adolescent mental health related to interpersonal trauma (IPT). Among those at highest risk for interpersonal violence and its sequelae are youth from urban, low-resourced neighborhoods. Post-traumatic stress disorder (PTSD) is a common outcome associated with IPT. Substance misuse (SUB) is a frequent concomitant of PTSD. NET is a promising intervention to reduce PTSD symptoms and associated psychological distress, via the supported reconstruction (narrative telling) of the traumas. NET has a critical advantage over existing PTSD treatments in that it can be delivered in a brief format, in community settings where at-risk adolescents are likely to be found. Despite its promise in treating adolescent distress, NET has yet to be tested as an intervention for those who have interpersonal trauma-related PTSD. Further NET's influence on SUB has not been examined.

Accordingly, the objective of this project is to conduct a pilot study (N=30) to estimate NET treatment effects on PTSD symptoms and SUB in IPT-exposed urban adolescents (ages 16-21). Both feasibility and preliminary efficacy data will be collected to serve as pilot work for a larger-scale NIH proposal. Recruitment and intervention will be set within community partners where the adolescents already are connected and are receiving social or psychological services. Outcome data will be collected at: (T0) Baseline, and at 1(T1), and 3 months (T2) follow-up assessments. Participant responses to the intervention will be assessed post-intervention. Change in PTSD, SUB will be estimated with effect sizes and inferential tests. Preliminary evidence of efficacy and feasibility will pave the way for further NET development to offer a patient-oriented, community-based, intervention that will promote adolescent mental health for those at greatest risk for health access and outcomes disparities.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adolescents (ages 16-25),
  • Positive PTSD diagnosis (CAPS diagnosis)
  • Positive lifetime incidence of interpersonal violence-related trauma.

Exclusion criteria

  • Actively suicidal with an immediate referral to the community agency crisis staff
  • Severe cognitive delay
  • Active psychosis

Treatment and study plan

Narrative Exposure Therapy

Behavioral

brief, trauma-focused treatment.

Other names: NET

Primary outcomes

  1. Posttraumatic Stress Disorder Checklist-Civilian Version

    Time frame: At baseline, at 1 month follow up, and at 3 month follow up

    assessed via PTSD checklist. The minimum score for this measure is 0 while the maximum is 80. Higher scores indicate more severe PTSD symptoms.

Secondary outcomes

  1. Alcohol Use Disorders Identification Test (AUDIT)

    Time frame: Only 1 participant finished the follow up for 1 month and 3 month (they are a different participant).

    alcohol use assessed via AUDIT. The minimum score for this measure is 0 while the maximum is 40. Higher scores indicate more alcohol use.

  2. Young Adult Alcohol Consequences Questionnaire (YAACQ)

    Time frame: Only 1 participant finished the follow up for 1 month and 3 month (they are a different participant).

    alcohol consequences assessed via YAACQ. The minimum score for this measure is 0 while the maximum is 48. Higher scores indicate more alcohol consequences.

Sponsors and collaborators

Lead sponsor

State University of New York at Buffalo

Other

Collaborators

  • National Center for Advancing Translational Sciences (NCATS)

Registry information

Acronym: POWER-NET

Important dates

Study start
2017
Primary completion
2021
Study completion
2021
First posted
Nov 9, 2018
Registry last updated
May 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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