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OpenTrials
Completed

NCT Number: NCT05531318

Emotional Regulation in People With Co-occurring Posttraumatic Stress Disorder and Substance Use Disorder

The aim of this project is to look at emotional regulation in people with posttraumatic stress disorder (PTSD) and substance use disorder (SUD). This study will explore how people with PTSD-SUD regulate their emotions and how this might explain the relationship between these two disorders. In turn, this may inform effective treatment strategies for people with comorbid PTSD-SUD.

Emotional regulation refers to the way in which people process and respond to their emotions. PTSD and SUD commonly cooccur and this is associated with adverse outcomes including high rates of relapse, overdose, and suicide. We therefore need effective treatments to address this clinical concern. Evidence suggests emotional regulation might be important in the development and maintenance of PTSD and SUD and therefore it might be a useful target for treatment. However, most research in this area has been quantitative and has not considered how gender, social circumstances and trauma or substance type might affect the way people regulate their emotions. This study will recruit 40 adults with trauma histories and PTSD who are currently receiving treatment in a community drug and alcohol service for their substance use. Participants will be interviewed to explore how they regulate their emotions and how this relates to their social circumstances. This study will also explore whether gender, substance or trauma type affect the way people regulate their emotions. We hope this will help to improve treatment for people with PTSD and SUD.

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Key information

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • • Adults aged 18+
  • Receiving treatment from a community substance use service at the time of the study.
  • Experienced, witnessed or been confronted with at least one traumatic event (according to PTSD Diagnostic Scale for DSM-5) (PDS-5) (Foa, 2016).
  • Participant endorses at least 3 PTSD symptoms from criterion B-E, measured using the PDS-5.
  • Able to communicate and understand English sufficiently to engage in a qualitative interview.

Exclusion criteria

  • • Staff recommend the individual should not take part in the study
  • The individual is unable to provide informed consent

Treatment and study plan

Qualitative interview

Other

Participants will be interviewed about their experiences of substance use, post-traumatic stress and the way they regulate their emotions.

Primary outcomes

  1. Qualitative interview accounts

    Time frame: November 2022 - October 2024

    Semi-structured interviews will be used

Sponsors and collaborators

Lead sponsor

King's College London

Other

Collaborators

  • Society for the Study of Addiction

Registry information

Official study title

Emotional Regulation in People With Co-occurring Posttraumatic Stress Disorder and Substance Use Disorder: A Qualitative Study of Individuals Receiving Community Substance Misuse Treatment

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Sep 7, 2022
Registry last updated
May 2, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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