Taipei Medical University Hospital
Taipei, Taiwan, 110
NCT Number: NCT02029755
Postoperative analgesia is an important part of the anesthetic care. According to the recent studies, multimodal analgesia can provide better analgesia & patient satisfaction with fewer side effect. For example, combining intravenous, intramuscular or oral analgesics with transversus abdominis plane (TAP) block or local anesthetic (LA) infiltration as the multimodal analgesia, can furnish a more effective pain control after the abdominal surgery.
For abdominal surgery, both local infiltration and TAP block target on relieving somatic pain. Local anesthetic wound infiltration is easy to perform with low risk. As the advancement of ultrasound technology, performing the TAP block also becomes easier, safer and more accurate. But whether LA infiltration or TAP block is better for the multimodal analgesia regimen remains unclear.
This study is to compare the postoperative pain score, opioid consumption, side effects, and quality of recovery between these two analgesic methods in patients undergoing abdominal surgery. The investigators hypothesized that TAP block may be more effective than LA infiltration as a part of the multimodal analgesia, and can improve the recovery after the abdominal surgery.
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Notify Me20 year–65 year
All sexes
Interventional
Not applicable
Taipei, Taiwan, 110
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
bilateral ultrasound-guided transversus abdominis plane block, with 20 ml of 0.25% ropivacaine at each side after the induction of general anesthesia
local anesthetics infiltration at surgical wound with 20 ml of 0.5% ropivacaine before wound closure
Other names: local anesthetics infiltration
postoperative analgesia with intravenous patient controlled analgesia with morphine
Time frame: postoperative 24 hour dynamic
pain scores of the participants will be followed at postoperative 1, 6, 24, 48 hour (up to 48 hours).
(NRS: from 0 to 10, 0 = no pain, 10 = the worst pain) The higher score idicates the worse outcome.
Time frame: postoperative 48 hour
opioid consumption of the participants will be followed at postoperative 1, 6, 12, 24, 36, 48 hour (up to 48 hours).
Time frame: postoperative 1, 6, 24, 48 hour
Time frame: postoperative 1, 6, 24, 48 hour
Time frame: postoperative 1, 6, 12, 24, 36, 48 hour
Time frame: postoperative 1, 6, 12, 24, 36, 48 hour
Time frame: an expected average of 5 days
participants will be followed for the duration of hospital stay
Time frame: postoperative 1, 6, 24, 48 hour
Time frame: postoperative 48 hour
Time frame: preoperative, postoperative 1 hour and 1 day
Time frame: an expected average of 5 days
participants will be followed for the duration of hospital stay
Time frame: an expected average of 5 days
participants will be followed for the duration of hospital stay
Time frame: an expected average of 5 days
participants will be followed for the duration of hospital stay
Taipei Medical University Hospital
Other
Ultrasound-guided-transversus Abdominis Plane(TAP) Block Versus Local Anesthetic(LA) Infiltration-the Effectiveness of Post-operative Pain Control in the Abdominal Surgery
Acronym: TAP
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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