Recruiting

NCT Number: NCT06905600

Transient Pseudohypoaldosteronism Affecting Children With Urinary Tract Malformation

Pseudohypoaldosteronism is a pathology affecting children under 6 months of age, little known but which can have serious consequences.

There are no real figures on the prevalence of this pathology in France. The exact pathophysiology is not known and the management is not currently codified.

This is why it is interesting to study this pathology and its treatment on a national scale in order to think about the best possible treatment, as well as to raise awareness of this pathology among different health professionals.

Recruiting

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Key information

Conditions

Pseudohypoaldosteronism Congenital, Hereditary, and Neonatal Diseases and Abnormalities Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genetic Diseases, Inborn Kidney Diseases Male Urogenital Diseases Renal Tubular Transport, Inborn Errors Urogenital Diseases Urologic Diseases

Age range

1 year–6 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Service pédiatrie 1 - CHU de Strasbourg - France

Strasbourg, 67091, France

Location status: Recruiting

Location contact

Ariane ZALOSZYC, MD

CONTACT

[email protected]

33 3 88 12 77 42

Ariane ZALOSZYC, MD

PRINCIPAL_INVESTIGATOR

Inès BERNHARD, MD

SUB_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Minor subjects aged less than 6 years at the time of diagnosis
Diagnosis of pseudohypoaldosteronism in the context of urinary malformation and/or urinary infection between January 1, 2018 and December 31, 2023
Subject (and/or their parental authority) having not expressed, after information, their opposition to the reuse of their data for the purposes of this research.

Exclusion criteria

Subject (or their parents) having expressed their (their) opposition to participating in the study

Treatment and study plan

Primary outcomes

National comparison of clinical and therapeutic practices concerning the management of pseudohypoaldosteronism in children with urinary malformations and/or urinary infections

Time frame: Up to 1 year

This study compares clinical and therapeutic practices

The retrospective analysis of the data will be carried out using classic statistical tests (Student's test, Fisher's test, ROC curve)

Study contacts

Contact information is provided by the study sponsor or research team.

Ariane ZALOSZYC, MD

CONTACT

[email protected]

33 3 88 12 77 42

Sponsors and collaborators

Lead sponsor

University Hospital, Strasbourg, France

Other

Registry information

Official study title

Transient Pseudohypoaldosteronism Affecting Children With Urinary Tract Malformation: Diagnosis and Management in a French Retrospective Study

Acronym: TPHA

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Apr 1, 2025
Registry last updated: Apr 1, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed