Skip to main content
OpenTrials
Enrolling by Invitation

NCT Number: NCT05653310

Tradipitant for Functional Dyspepsia

To evaluate the effects of tradipitant relative to placebo on gastric motor functions, satiation, and postprandial symptoms in patients with functional dyspepsia.

Enrolling by Invitation

Interested in participating?

Request Info

Key information

Conditions

Functional Dyspepsia

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Mayo Clinic in Minnesota

Rochester, Minnesota, 55905, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Able to provide written consent
  • Body Mass Index (BMI) of 18-35 kg/m2
  • Absence of other diseases which could interfere with interpretation of study results

Exclusion criteria

  • Current H. pylori infection
  • Pregnancy or nursing
  • Recent history of Alcohol Use Disorder or Substance Use Disorder

Treatment and study plan

Tradipitant

Drug

Tradipitant Capsule

Placebo

Drug

Placebo Capsule

Primary outcomes

  1. Accommodation gastric volumes measured by single photon emission computed tomography (SPECT)

    Time frame: 4 Weeks

Sponsors and collaborators

Lead sponsor

Xiao Jing (Iris) Wang

Other

Collaborators

  • Mayo Clinic

Registry information

Official study title

Pharmacodynamics, Pharmacogenetics, Clinical Efficacy and Safety of Tradipitant for Functional Dyspepsia

Important dates

Study start
2023
Primary completion
2027
Study completion
2027
First posted
Dec 16, 2022
Registry last updated
Jul 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.