Tracheal Anatomy After Thyroidectomy

The investigators aimed at investigating the effects of thyroidectomy on tracheal anatomy and airflow in patients with benign nodular goiter, employing a prospective observational study.

Magnetic resonance images of the neck and respiratory flow-volume curves were performed prior to and six months following surgery. Tracheal and thyroid volumes, smallest cross-sectional area of the trachea (SCAT), tracheal narrowing, tracheal deviation and tracheal encirclement by the thyroid were evaluated. Through flow-volume curves respiratory function, including both in- and expiration, was evaluated.

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Key information

Conditions

Goiter, Nodular Endocrine System Diseases Goiter Thyroid Diseases

Age range

20 year–80 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Reads and write Danish

Exclusion criteria

Suspected or present malignancy
Neuromuscular disease
Prior surgery to the neck

Treatment and study plan

Thyroidectomy

Procedure

Remove the nodular goiter on the neck by thyroidectomy (standard procedure)

Primary outcomes

Changes in tracheal anatomy

Time frame: 6 months follow-up

Change in tracheal narrowing (cross sectional area of the trachea at the goiter level compared to cross-sectional area of the trachea at the carina)

Sponsors and collaborators

Lead sponsor

University of Southern Denmark

Other

Registry information

Official study title

Thyroidectomy Improves Tracheal Anatomy and Airflow in Patients With Nodular Goiter: A Prospective Cohort Study

Important dates

Study start: 2014
Primary completion: 2017
Study completion: 2017
First posted: Mar 7, 2017
Registry last updated: Mar 7, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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