Skip to main content
OpenTrials
Completed

NCT Number: NCT05220969

Total Genotype Score, Growth, Maturation and Loading Exposure as Risk Factors for Injury in Elite Male Youth Football

A total genotype risk score was generated based on the findings of previous research for non-contact injury, non-contact muscle injury, tendon injury, ligament injury, fracture injury and apophysitis injury. This score was then compared with the incidence of injury between those with high, medium and low risk scores for each injury. The influence of different rates of growth, stages of physical maturation and loading exposure were then also included in the risk model to see if any interaction effects could be observed between genetic risk score and susceptibility to injury in different categories of growth, maturation and loading exposure.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Fractures in Children Apophysitis Disease Attributes Disease Susceptibility Genetic Predisposition Genetic Predisposition to Disease Ligament Injury Muscle Strain Pathologic Processes Pathological Conditions, Signs and Symptoms Sprains and Strains Tendon Injuries Wounds and Injuries

Age range

12 year–40 year

Sex eligibility

Male

Study type

Observational

Primary location

Fulham Football Club, London, New Malden, United Kingdom

Loading trial locations.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Elite male football players

Exclusion criteria

  • Female
  • non-elite

Treatment and study plan

Total Genotype Risk Score

Genetic

A total genotype risk score has been generated based on the results of previously observed genetic association studies

Primary outcomes

  1. Fracture Injury Risk

    Time frame: 8 Years

    Did the risk of fracture differ between total genotype risk score categories? was this affected by maturation?

  2. Non-Contact Injury Risk

    Time frame: 8 Years

    Did the risk of non-contact injury differ between total genotype risk score categories? was this affected by maturation, and loading?

  3. Non-Contact Muscle Injury Risk

    Time frame: 8 Years

    Did the risk of non-contact muscle injury differ between total genotype risk score categories? was this affected by maturation, and loading?

  4. Tendon Injury Risk

    Time frame: 8 Years

    Did the risk of tendon injury differ between total genotype risk score categories? was this affected by maturation, and loading?

  5. Ligament Injury Risk

    Time frame: 8 Years

    Did the risk of ligament injury differ between total genotype risk score categories? was this affected by maturation?

  6. Apophysitis Injury Risk

    Time frame: 8 Years

    Did the risk of ligament injury differ between total genotype risk score categories? was this affected by maturation?

Sponsors and collaborators

Lead sponsor

St Mary's University College

Other

Collaborators

  • Fulham Football Club

Registry information

Important dates

Study start
2019
Primary completion
2021
Study completion
2021
First posted
Feb 2, 2022
Registry last updated
Feb 2, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.