Dating of Child Fractures : Chronological Repers From the Radiological Evolution of a Series of Femur Fractures

Although several studies have studied the predictive nature of non-accidental trauma of the different types of fractures and in particular on the femur, the physiological and radiological particularities of the child make it difficult to estimate the age of a fracture and require defining a chronology specific to the specificities of the pediatric population. Some authors have carried out work for the dating of fractures, however the number of cases or the average age of the subjects does not allow a precise estimation of the chronology of evolution of the fractures.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Fractures in Children Callosities Femoral Fractures Fractures, Bone Keratosis Leg Injuries Skin Diseases Skin and Connective Tissue Diseases Wounds and Injuries

Age range

1 year–17 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Service de Chirurgie Orthopédique Pédiatrique - CHU de Strasbourg - France

Strasbourg, 67091, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Child aged 18, cared for in the pediatric orthopedic department of the Strasbourg University Hospitals between January 2007 and December 2020
Fracture of the femur resulting from orthopedic treatment instituted during a period of hospitalization
Holders of parental authority who have been informed of the use of their child's data for the purposes of this research and who have not expressed any opposition

Exclusion criteria

Patient or legal representative who expressed their opposition to participating in the study
Fracture of the femur having benefited from a surgical intervention
Weakening metabolic or bone pathology
Fracture on pathological focal lesion
Fractures of the epiphysis or affecting the growth cartilage
Impossibility of giving informed information to the subject

Treatment and study plan

Primary outcomes

Define retrospectively the chronology of the appearance of periosteal callus, secondary callus and remodeling phenomena from the study of radiographs of the femur

Time frame: Files analysed retrospectively from January 01, 2007 to December 31, 2020 will be examined
Evaluation of the time to radiographic appearance of the following stages defined by the number of days elapsed between the date of diagnosis of the fracture and the first radiography taken during follow-up, making it possible to highlight one of these phenomena:
- The radiographic periosteal reaction (or periosteal callus) defined by an opacity at the periphery of the fracture, corresponding to the first objectifiable calcification of the fracture hematoma and under the periosteum.
- The secondary bone callus (or osteochondral) defined by a well-defined bone apposition of density close to that of the bone with opacification of the fracture line and union of the fracture site
- Established remodeling activity when phenomena of axis correction, resorption of initial callus hypertrophy or re-permeabilizatio of the diaphyseal shaft can be demonstrated

Sponsors and collaborators

Lead sponsor

University Hospital, Strasbourg, France

Other

Registry information

Acronym: DFE

Important dates

Study start: 2020
Primary completion: 2022
Study completion: 2022
First posted: Nov 22, 2022
Registry last updated: Nov 2, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed