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OpenTrials
Completed

NCT Number: NCT01179763

Thickness of Retinal Layers in Amblyopia

The purpose of this study is to examine retinal layer thickness in amblyopia.

Completed

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Key information

Conditions

Amblyopia Brain Diseases Central Nervous System Diseases Eye Diseases Nervous System Diseases Neurologic Manifestations Pathological Conditions, Signs and Symptoms Sensation Disorders Signs and Symptoms Vision Disorders

Age range

4 year–19 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Samsung Medical Center

Seoul, South Korea

About this study

Amblyopia is a visual disorder characterized by a reduction of vision that cannot be immediately improved by refractive correction or accounted for by clinically determined anatomic defects of the eye or visual pathway. Evidence for direct retinal changes in eyes with amblyopia has been controversial. It has been hypothesized that amblyopia may affect the postnatal maturation of the retina including the postnatal reduction of retinal ganglion cells. However, although some studies have found incrased retinal nerve fiber layer thickness in amblyopic eyes, others have found no significant differences. This sutdy will examine the retinal layer thickness in amblyopia and compare the retinal layer thickness between amblyopic eyes and nonamblyopic fellow eyes.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Amblyopia

Exclusion criteria

  • Other retinal disease
  • Anisometropia
  • Neurologic abnormalities

Treatment and study plan

optical coherence tomography

Other

Spectral domain optical coherence tomography will be conducted once when patients are enrolled.

Other names: Spectralis Optical coherence tomography

Primary outcomes

  1. Retinal layer thickness

    Time frame: One month

    Optical coherence tomography scan will be conducted to analyze retinal layer thickness, when the patient are enrolled.

Sponsors and collaborators

Lead sponsor

Samsung Medical Center

Other

Registry information

Official study title

Analysis of Spectral Domain Optical Coherence Tomography Measurements in Amblyopia

Important dates

Study start
2010
Primary completion
2010
Study completion
2010
First posted
Aug 11, 2010
Registry last updated
Aug 11, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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