Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07192887

Thebaine Urine Testing

To develop and validate a urine drug screen to detect thebaine.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Urine Specimen Collection

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States

Location status: Recruiting

Location contact

Charlotte Walter, MD

CONTACT

[email protected]

513-636-4408

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male or female
  • Ages 18-65
  • Healthy

Exclusion criteria

  • Allergy to poppy seeds, or any of the related food stuffs used in the study
  • Celiac disease or gluten sensitivity
  • Ongoing or opioid use in the past 6 months
  • History of renal or hepatic disease or dysfunction
  • Inability or unwillingness to give repeated urine specimens
  • Unwillingness to refrain from eating poppy seed-containing products during the two-day course of the study
  • Non-English speakers (due to study materials being in English)
  • BMI greater than 30
  • Antibiotic use in the previous 2 months
  • Recent ingestion of poppy seeds from the previous 7 days

Treatment and study plan

Primary outcomes

  1. Validate thebaine urine screen

    Time frame: Enrollment to 48 hours after enrollment

    Validate a liquid chromatography-tandem mass spectrometry method to detect thebaine in urine

Study contacts

Contact information is provided by the study sponsor or research team.

Charlotte Walter, MD

CONTACT

[email protected]

513-636-4408

Sponsors and collaborators

Lead sponsor

Children's Hospital Medical Center, Cincinnati

Other

Registry information

Official study title

Clinical Feasibility of Thebaine Urine Mass Spectrometry Drug Testing

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Sep 25, 2025
Registry last updated
Sep 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.