Skip to main content
OpenTrials
Completed

NCT Number: NCT03273010

The Use of Cyanoacrylate on Palatal Wound

The palatal donor site of autogenous free gingival grafts significantly influences the patient's morbidity. The purpose of this study was to evaluate the efficacy of cyanoacrylate on palatal wound healing and postoperative complaints.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Gingival Recession Gingival Diseases Mouth Diseases Periodontal Atrophy Periodontal Diseases Stomatognathic Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

A total of 35 patients were included in the study. In the test group (19 patient), cyanoacrylate was placed over the palatal wounds; conversely, the 16 control group patients were allowed to heal in a conventional way without cyanoacrylate.

Primary bleeding time, presence of secondary bleeding, postoperative pain and completion of epithelization were assessed following free gingival graft operation. As a result, compared to the control group it was determined that the cyanoacrylate tissue adhesive could reduce the postoperative morbidity and improve the wound healing.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • no systemic diseases
  • no coagulation disorders
  • no drug intake in the previous 6 months that might effect the periodontal health status
  • no pregnancy or lactation
  • no smoking habit
  • <1 mm attached gingiva width on one or two lower anterior teeth
  • Miller Class I- II- III (Miller 1985) with deep gingival recession (˃ 3mm)

Exclusion criteria

  • Hematologic disorders
  • No cooperation

Treatment and study plan

Free gingival graft

Procedure

Free gingival graft was harvested from palatal donor site

Cyanoacrylate application

Procedure

Periacyrl was applied on palatal wounds

Primary outcomes

  1. Primary bleeding time

    Time frame: baseline

    The moment of active blood flow stasis that a clinical photograph could be taken by examiner without need for suction.

Secondary outcomes

  1. Visual Analog Scale (VAS)

    Time frame: 1-7 days after operation

    The changes in postoperative pain level after the operation

  2. Analgesic consumption

    Time frame: 1-7 days after operation

    The changes in the number of painkiller taken to relieve pain after the operation

  3. Completion of epithelization

    Time frame: Once a week for a month after the operation

    The epithelization assessed by the peroxide test

Sponsors and collaborators

Lead sponsor

Ordu University

Other

Registry information

Official study title

The Efficacy of Cyanoacrylate on Palatal Wound Healing and Postoperative Complaints

Important dates

Study start
2015
Primary completion
2016
Study completion
2016
First posted
Sep 6, 2017
Registry last updated
Sep 6, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.