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OpenTrials
Completed

NCT Number: NCT02263963

The Transversus Abdominis Plane Block: A Prospective Randomized Clinical Trial Using EXPAREL.

The purpose of the study is to evaluate the effectiveness of EXPAREL in a transversus abdominis plane block by assessing the demand of postoperative narcotic, length of hospital stay and incidence of postoperative complications.

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Key information

Conditions

Postoperative Pain Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Spectrum Health

Grand Rapids, Michigan, 49503, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients over the age of 18 years w
  • Elective laparoscopic colorectal resection.

Exclusion criteria

  • Patients under 18 years.
  • Patients unable to provide informed consent
  • Patients undergoing emergency surgery.
  • Pregnant women
  • Severe liver or kidney disease (GFR 15-29 ml/min)

Treatment and study plan

Exparel

Drug

In this arm as described above the intervention will be TAP block injection under ultrasound guidance using Exparel.

TAP Block

Procedure

no intervention will be done to this arm.

Primary outcomes

  1. Postoperative Pain Score

    Time frame: participants will be followed for the duration of hospital stay, an expected average of 4 days

    Patient will be evaluate for their post operative pain by nurses using visual analog scale from 0 to 10, zero means no pain, 10 is the worst pain can patient ever experience.

Secondary outcomes

  1. Postoperative Narcotic Use

    Time frame: participants will be followed for the duration of hospital stay, an expected average of 4 days

    Will be measured, by converting all narcotic medicine used during postoperative period to equal morphine in mg, a calculator created by our pharmacy expert is able to convert any narcotic medicine such as fentanyl, oxycodone, hydromorphone, to morphine in mg. By doing that will have one variable to compare to the two groups.

Other outcomes

  1. Postoperative Complications.

    Time frame: participants will be followed for the duration of hospital stay, and 30 days after discharge.

    Any postoperative complications within 30 days of procedure, including death will be recorded.

  2. Length of Hospital Stay.

    Time frame: participants will be followed for the duration of hospital stay, an expected average of 4 days

    Length of hospital stay will be measured in number of days patient spends in the hospital from the day of procedure till discharge.

Sponsors and collaborators

Lead sponsor

Corewell Health West

Other

Registry information

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
Oct 15, 2014
Registry last updated
Feb 28, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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