Recruiting

NCT Number: NCT06765850

The Study Aims to Measure the Metabolome in Melanoma Patients Using NMR Spectroscopy and Gas Chromatography and to Analyse Differences Depending on the Course of the Disease.

Prospective, single-centre study with the central question of how the metabolome from blood samples, different body fluids and tissues between patients patients with malignant melanoma in different tumour tumour stages and healthy patients and whether this is suitable for early detection of initial diagnosis, recurrence or stage shift at an early stage.

The biosamples are collected in the BioBank Dresden and used for the NMR and LC-MS analyses described here. It is planned to use the biosamples for further analyses.

Recruiting

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Key information

Conditions

Melanoma of Skin Melanoma Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Germ Cell and Embryonal Neoplasms, Nerve Tissue Neuroectodermal Tumors Neuroendocrine Tumors Nevi and Melanomas Skin Diseases Skin Neoplasms Skin and Connective Tissue Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital Carl Gustav Carus

Dresden, Saxony, 01307, Germany

Location status: Recruiting

Location contact

Frank Friedrich Gellrich, Dr. med.

CONTACT

[email protected]

+493514582497

Frank Friedrich Gellrich, Dr. med.

CONTACT

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Current or past history of melanoma
Ongoing therapy or tumour aftercare at the Skin Cancer Centre at Dresden University Hospital

Exclusion criteria

Refusal to participate in the study
Lack of capacity to consent

Treatment and study plan

Primary outcomes

Differences in metabolite concentrations

Time frame: through study completion, an average of 3 years

Metabolite concentrations are measured by NMR spectroscopy and gas chromatography and compared between different subgroups.

Study contacts

Contact information is provided by the study sponsor or research team.

Frank Friedrich Gellrich, Dr. med.

CONTACT

[email protected]

+493514582497

Sponsors and collaborators

Lead sponsor

Technische Universität Dresden

Other

Collaborators

University Hospital Carl Gustav Carus

Registry information

Official study title

Measurement of the Metabolome in Melanoma Patients Using NMR Spectroscopy and Gas Chromatography.

Important dates

Study start: 2022
Primary completion: 2026
Study completion: 2027
First posted: Jan 9, 2025
Registry last updated: Jan 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting