University of Nevada, Reno
Reno, Nevada, 89557, United States
Location status: Recruiting
Location contact
Cynthia L Lancaster, PhD
CONTACT
NCT Number: NCT05558527
This study will examine the effects of social support on threat vigilance and arousal using eye tracking. We will also test the moderating effects of trauma and discrimination history.
Interested in participating?
Request Info18 year–65 year
All sexes
Interventional
Not applicable
Reno, Nevada, 89557, United States
Location status: Recruiting
Cynthia L Lancaster, PhD
CONTACT
Both interpersonal trauma (IPT) and ethno-racial discrimination amplify risk for hyper-arousal symptoms of posttraumatic stress disorder (PTSD), but the mechanism of this effect is unclear. Prior research suggests that social support plays an important role in regulating emotional responses, a process called social emotion regulation. This study will test whether a history of IPT and/or ethno-racial discrimination influence the social regulation of arousal and vigilance. Social regulation will be tested by contrasting responses under conditions with and without social support.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
social support is provided in the form of social touch (hand holding)
Time frame: Collected from minute 15 to minute 45 of study participation, approximately
Participants will view 15 pictures of natural environmental scenes for 10 seconds per image. We will use an eye tracker to examine the number of eye fixations per scene. A greater number of fixations during the 10 second presentation of a scene would indicate greater vigilance.
Time frame: Collected from minute 15 to minute 45 of study participation, approximately
Participants will view 15 pictures of natural environmental scenes for 10 seconds per image. We will use an eye tracker to examine the proportion of the scene that they look at (fixate on) out of approximately 80 possible sectors. A greater proportion of the scene they fixate on would indicate greater vigilance.
Time frame: Collected from minute 45 to minute 75 of study participation, approximately
Participants will view a series of visual cues (either an 'X' or an 'O') where an 'X' signals a possible (20% probability) aversive auditory stimulus (human scream). We will examine pupil dilation during the task in order to measure arousal in response to uncertain threat. We will calculate average pupil dilation during the wait period after threat cues (X) and after safety cues (O). We will subtract average pupil dilation after safety cues from threat cues to create an index of threat-related arousal. Greater pupil dilation (for threat minus safety cues) would indicate greater threat-related arousal.
Contact information is provided by the study sponsor or research team.
Cynthia L Lancaster, PhD
CONTACT
Kylie Baer, MS
CONTACT
University of Nevada, Reno
Other
Effects of Trauma and Discrimination on the Social Regulation of Threat-related Vigilance and Arousal
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT06608706
Historical Trauma, Mental Disorders
Bergen, Norway
View Trial DetailsNCT06864637
Combat Disorders, Historical Trauma
Tampa, Florida, United States
View Trial DetailsNCT07546266
Behavior, Historical Trauma
Akron, Ohio, United States
View Trial DetailsNCT05264415
Anxiety, Anxiety Disorders
Los Angeles, California, United States
View Trial Details