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Completed

NCT Number: NCT06915051

The Relationship Between Umbilical Cord Coiling Index and Fetal Cardiac Functions.

The maximum efficiency of umbilical cord blood flow depends on a specific number of coils. With modern ultrasound techniques, investigators can now detect cord abnormalities even before birth. In recent years, there has been a renewed interest in the umbilical cord, and several articles have been published regarding the number of coils.In this study, the relationship between the umbilical cord coiling index and fetal cardiac functions was evaluated.

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Key information

Conditions

Umbilical Cord Coiling Index and Fetal Cardiac Functions Congenital, Hereditary, and Neonatal Diseases and Abnormalities Hypertension, Pulmonary Infant, Newborn, Diseases Lung Diseases Persistent Fetal Circulation Syndrome Respiratory Tract Diseases

Age range

18 year–50 year

Sex eligibility

Female

Study type

Observational

Primary location

Sanliurfa Education and Research Hospital

Sanliurfa, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

-Singleton uncomplicated pregnancies between 20-24 weeks seeking routine antenatal care.

Exclusion criteria

  • Multiple pregnancy
  • Preterm rupture of membranes
  • Chorioamnionitis
  • Placental abruption
  • Severe fetal growth restriction
  • Congenital anomalies of the fetus
  • Preeclampsia
  • Oligohydramnios
  • Maternal diabetes.

Treatment and study plan

Determining the relationship between the coiling number and fetal echocardiography findings.

Diagnostic Test

Fetal echocardiography findings to be performed simultaneously with the determination of the coiling number.

Primary outcomes

  1. The correlation between the fetal umbilical cord coiling number and the concurrently performed fetal echocardiography findings.

    Time frame: The correlation between the fetal umbilical cord coiling index and the echocardiographic findings of the fetus within the first hour will be investigated.

    This study will be a single-center study conducted on two hundred randomly selected pregnant women with uncomplicated singleton pregnancies in the late second trimester (20-24 weeks) who visit our hospital's perinatology outpatient clinic for routine prenatal check-ups. The umbilical cord coiling number and fetal cardiac function measurements will be performed within one hour by the same maternal-fetal medicine specialist.To optimize the quality of Doppler waveforms when assessing vascular structures, measurements will be obtained in the absence of uterine contractions and fetal activity, with an insonation angle as close to zero as possible and less than 30.Three parameters will be used to assess cardiac function:

    • Diastolic function
    • Systolic function
    • Both systolic and diastolic function

Sponsors and collaborators

Lead sponsor

Sanliurfa Education and Research Hospital

Other Gov

Registry information

Official study title

Evaluation of the Relationship Between Umbilical Cord Coiling Index and Fetal Cardiac Functions.

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Apr 8, 2025
Registry last updated
Nov 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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