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NCT Number: NCT07677969

The Relationship Between Lost Extremity Percentage and Postural Control, Neck and Low Back Pain, Daily Living Activities, and Reaction Time in Individuals With Unilateral Upper Limb Amputation

This observational study aims to examine the relationship between the percentage of limb loss and functional outcomes in individuals with unilateral upper limb amputation. Upper limb amputation can affect posture, balance control, pain levels, daily living activities, hand function, and reaction time. However, limited research has investigated how the amount of limb loss influences these outcomes.

Participants between 18 and 65 years of age who use a myoelectric or bionic prosthesis will undergo a series of assessments. These assessments include measurements of postural control using a force platform, posture analysis, evaluation of neck and low back pain using a visual analog scale, daily living activities using a validated questionnaire, hand dexterity using the Box and Block Test, and reaction time using a visual stimulus device.

The study does not involve any intervention or treatment. All evaluations will be performed during a single assessment session. The results of this study may help improve rehabilitation planning and provide better understanding of functional changes associated with different levels of limb loss in people with upper limb amputation.

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Key information

Conditions

Upper Limb Amputation Back Pain Daily Activities Low Back Pain Neck Pain Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Postural Control Reaction Time Signs and Symptoms

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged 18-65 years
  • Unilateral upper limb amputation
  • Use of a myoelectric or bionic prosthesis for at least 1 year
  • Current prosthesis use for a minimum of 3 months

Exclusion criteria

  • Bilateral upper limb amputation
  • Additional amputation of another limb
  • Use of passive or cosmetic prosthesis
  • Presence of neurological or other significant orthopedic disorders unrelated to amputation

Treatment and study plan

This is an observational study. No interventional procedures are performed. All assessments are non-invasive measurements.

Other

This is an observational study. No interventional procedures are performed. All assessments are non-invasive measurements.

Primary outcomes

  1. Daily living activity score

    Time frame: through study completion, an average of 1 year

    In upper extremity amputees, daily living activities and occupational skills will be assessed using a questionnaire. (0-100 score, Survey on Activities of Daily Living and Occupations of Upper Extremity Amputees)

Secondary outcomes

  1. Postural Sway and Limits of Stability

    Time frame: through study completion, an average of 1 year

    Postural sway (cm) measured using a force BERTEC platform system.

  2. Postural Sway and Limits of Stability

    Time frame: through study completion, an average of 1 year

    limits of stability (%) measured using a force BERTEC platform system.

  3. Neck and Back Pain Intensity

    Time frame: through study completion, an average of 1 year

    Measured using the Visual Analog Scale (VAS) on a 0-10 scale, where 0 indicates no pain and 10 indicates the worst possible pain.

  4. Hand Dexterity

    Time frame: through study completion, an average of 1 year

    easured using the Box and Block Test (number of blocks successfully transferred from one compartment to another in 60 seconds).

  5. Reaction Time

    Time frame: through study completion, an average of 1 year

    Measured using the BlazePod system (recorded in milliseconds and the number of correct responses in 30 seconds).

Study contacts

Contact information is provided by the study sponsor or research team.

ASLI BEBEK, MSc

CONTACT

[email protected]

+905364037230

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jul 1, 2026
Registry last updated
Jul 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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