Gazi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation
Ankara, Turkey (Türkiye)
NCT Number: NCT03255460
Multiple sclerosis (MS) is a chronic, progressive and unpredictable disease of the central nervous system. In MS, various loss of strength, balance and gait disturbances arise in the central nervous system due to sensory and/or motor neuron degeneration. These disorders lead to limitations in individual activities and participation.
Fatigue is as reported one of the most common first three symptoms among patients with MS and affects up to 80% of the patients. Fatigue is defined as the lack of physical and/or mental energy. Sometimes fatigue can reduce the quality of life by leaving other disorders behind. The most important effect of fatigue is that individuals reduce their physical activity levels. This can lead to the inactivity-related secondary problems being added to the findings of the disease. So the physical capacities of individuals may gradually decrease.
In the literature, there are many studies showing that the level of physical activity of individuals with MS is lower than in healthy individuals. When the investigators analyze the studies that investigate the relation between fatigue and physical activity levels, it is seen that there is the single study about this subject in the literature.
As a result, additional studies are needed to investigate the level of physical activity and the factors affecting it in individuals with MS. Therefore, the investigators planned this study to investigate the relationship between fatigue and physical activity levels in patients with MS.
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Notify Me18 year–65 year
All sexes
Observational
Ankara, Turkey (Türkiye)
According to sample size calculation 37 diagnosed Multiple Sclerosis patients and 37 healthy individuals will be included.The demographic characteristics of the participants initially will be taken and Expanded Disability Status Scale score of those of MS will be recorded. Then, fatigue severity and perception, physical activity level, balance, peripheral muscle strength, functional mobility, functional exercise capacity will be evaluated. Primary outcomes are fatigue and physical activity level; secondary outcomes are balance, peripheral muscle strength, functional mobility, functional exercise capacity.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Time frame: Five minutes
Fatigue Severity Scale
Time frame: Eight minutes
Fatigue Impact Scale
Time frame: Three days
Evaluated using an ActiGraph (GT3X+)
Time frame: Five minutes
International Physical Activity Questionnaire
Time frame: Fifteen minutes
Evaluated using 6-minute walking test
Time frame: Fifteen minutes
Evaluated using Bio Sway [(BSS) Biodex Inc.,Shirley, New York]
Time frame: Two minutes
Evaluated using Time and Go test
Time frame: Fifteen minutes
Evaluated using digital hand dynamometer
Gazi University
Other
Investigation of the Relationship Between Fatigue and Physical Activity Level in Patients With Multiple Sclerosis
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